Doxycycline hyclate CAS: 24390-14-5 99% Yellow crystalline hmoov
| Catalog Number | xwm 90368 |
| Khoom npe | Doxycycline hyclate |
| CAS | 24 390-14-5 |
| Molecular Formula | C22H24N2O8 · HCl · 0.5C2H6O · 0.5H2O |
| Molecular Luj | 512.94 ib |
| Cov ntaub ntawv khaws cia | 2 txog 8 ° C |
| Harmonized tariff Code | 29413 000 Nws |
Khoom Specification
| impurity A | <2% |
| impurityB | <2% |
| Kev sib hloov tshwj xeeb | -105-120 |
| pH | 2-3 |
| Cov impurity C | <0.5% |
| impurityD | <0.5% |
| Poob rau ziab | 1.4-2.8% |
| Assay | 99% |
| Residue ntawm Ignition | <0.4% |
| Absorbtivity | 300-335 : kuv |
| Lwm yam impurity | <0.5% |
| Qhov tshwm sim | Yellow crystalline hmoov |
| impurity F | <0.5% |
| impurityE | <0.5% |
| Ethyl cawv | 4.5 - 6% |
| Absorbency ntawm impurity | <0.07% |
Kev tsim biofilm ntawm kev kho hniav tuaj yeem ua rau peri-implant mucositis thiab tom qab peri-implantitis.Cov mob no tau kho nrog tshuaj tua kab mob xws li doxycycline (Doxy).Ntawm no peb siv cov txheej txheem electrochemical ntawm cathodic polarization los tsho Doxy mus rau sab nrauv ntawm cov khoom siv kho hniav.Doxy-coated nto pom qhov tawg tawm hauv phosphate-buffered saline thaum thawj 24 teev.Txawm li cas los xij, ib qho tseem ceeb ntawm Doxy tseem nyob ntawm qhov chaw tsawg kawg 2 lub lis piam tshwj xeeb tshaj yog nyob rau ntawm 5 mA-3 h cov qauv nrog ntau dua Doxy tus nqi, tawm tswv yim ob qho tib si thawj zaug thiab lub sij hawm ntev bacteriostatic peev xwm ntawm coated nto.Surface chemistry tau txheeb xyuas los ntawm x-ray photoelectron spectroscopy thiab theem nrab ion huab hwm coj spectrometry.Surface topography tau soj ntsuam los ntawm qhov chaw emission scanning electron microscopy thiab xiav-light profilometry.Lub sijhawm polarization ntev dua ntawm 1 h txog 5 h thiab siab dua tam sim no los ntawm 1 txog 15 mA cm (-2) ua rau Doxy ntau dua ntawm cov nthwv dej ce.Qhov saum npoo tau npog los ntawm ib txheej ntawm Doxy tsawg dua 100 nm yam tsis muaj kev hloov pauv tseem ceeb hauv qhov chaw saum npoo av.Cov cuab yeej siv tshuaj tua kab mob ntawm Doxy-coated nto tau txheeb xyuas los ntawm biofilm thiab planktonic kev loj hlob kev soj ntsuam siv Staphylococcus epidermidis.Doxy-coated kuaj txo ob qho tib si biofilm tsub zuj zuj thiab planktonic kev loj hlob hauv cov kab lis kev cai, thiab tseem inhibited kab mob loj hlob ntawm agar daim hlau.Cov tshuaj tua kab mob muaj zog dua rau cov qauv ntawm 5 mA-3 h coated nrog ntau dua ntawm Doxy piv rau 1 mA-1 h.Yog li ntawd, ib qho abutment nto coated nrog Doxy muaj peev xwm tiv thaiv kab mob colonization thaum raug rau qhov ncauj kab noj hniav.Doxy-txheej txheem tuaj yeem yog txoj hauv kev siv tau los tswj peri-implant mucositis thiab tiv thaiv nws txoj kev loj hlob mus rau peri-implantitis.
