Cov khoom

Txhawm rau tshawb xyuas cov kab mob sib kis ntawm cov kab mob sib kis ntawm Neisseria gonorrhoeae los ntawm Saskatchewan, Canada, siv Neisseria gonorrhoeae multi antigen sequence typing (NG-MAST), thiab ntsuas kev koom tes ntawm cov tshuaj tiv thaiv kab mob tiv thaiv kab mob (AMS) thiab hom kab mob tshwj xeeb (STs).320 sib law liag. , sau los ntawm 2003 thiab 2008, tau ntaus los ntawm NG-MAST.STs tau pab pawg yog tias ib qho ntawm lawv cov alleles muaj ntau thiab lwm qhov txawv ntawm ≤1% hauv DNA ib ntus.AMS tau txiav txim siab los ntawm agar dilution (CLSI) rau xya cov tshuaj tua kab mob.N gonorrhoeae cais tawm rau hauv 82 tus neeg NG-MAST STs thiab 18 NG-MAST ST pawg nrog pawg 25, 3655, 921, 3654, 3657 thiab 3656 suav nrog 51. /320) ntawm kev cais.N gonorrhoeae isolates susceptible to all the tested antimicrobials are significantly (p<0.05) txuam nrog ST 25 (87%).Lwm cov koom haum tseem ceeb ntawm ST thiab AMS suav nrog: ST 3654 thiab cais nrog qhov tsawg kawg nkaus inhibitory concentrations ntawm ≥0.03 mg / L rau peb tiam ceph alosporins;ST 3711 (100%) thiab TRNG;thiab ST / pawg 3654 (43%) thiab chromosomal tsis kam rau penicillin thiab tetracycline.Ob peb NG-MAST STs / pawg tau cuam tshuam nrog kev sib cais nrog chromosomal tsis kam rau tetracycline.Isolates resistant rau ciprofloxacin (n=5) thiab azithromycin (n=2) tshwm sim raws li ib tug neeg STs.Cov koom haum tseem ceeb tau raug pom ntawm ib tus neeg STs, poj niam txiv neej thiab hnub nyoog ntawm tus neeg mob, thiab kev faib tawm hauv cheeb tsam thiab lub sijhawm.Kev sib koom ua ke ntawm N gonorrhoeae AMS thiab NG-MAST STs tau txheeb xyuas thiab tej zaum yuav muaj txiaj ntsig zoo hauv kev kwv yees AMS hauv cheeb tsam.Vim tias STs hauv ntau lub tebchaws sib txawv heev, kev siv NG-MAST rau kev kwv yees ntawm AMS thoob ntiaj teb yuav tsum tau kawm ntxiv.