Cov khoom

Cystic fibrosis yog ib hom kab mob caj ces uas ua rau cov hnoos qeev txawv txav hauv lub ntsws cuam tshuam nrog kev raug mob mus tas li.Pulmonary exacerbations yog thaum cov tsos mob ntawm tus kab mob hnyav dua.Cov tshuaj tua kab mob yog ib feem tseem ceeb ntawm kev kho mob rau exacerbations thiab inhaled tshuaj tua kab mob yuav siv tau ib leeg los yog ua ke nrog cov tshuaj tua kab mob qhov ncauj rau me ntsis exacerbations los yog intravenous tshuaj tua kab mob rau cov kab mob hnyav dua.Cov tshuaj tua kab mob uas nqus tau tsis ua rau muaj kev cuam tshuam zoo ib yam li cov tshuaj tua kab mob hauv cov hlab ntsha thiab tuaj yeem ua pov thawj lwm txoj hauv kev rau cov neeg uas tsis muaj kev nkag mus rau lawv cov hlab ntsha. Los txiav txim siab seb kev kho mob ntawm cov hlab ntsws exacerbations nrog cov tshuaj tua kab mob hauv cov neeg mob cystic fibrosis txhim kho lawv lub neej zoo, txo lub sijhawm so. tsev kawm ntawv lossis kev ua haujlwm thiab txhim kho lawv txoj sia nyob mus ntev.Peb tau tshawb nrhiav ClinicalTrials.gov thiab Australia thiab New Zealand Clinical Trials Registry rau cov kev sim uas cuam tshuam.Hnub kawg ntawm kev tshawb fawb: 15 Lub Peb Hlis 2012Peb kuj tau tshawb xyuas Cochrane Cystic Fibrosis G roup's Cystic Fibrosis Trials Register.Hnub kawg ntawm kev tshawb fawb: 01 Lub Rau Hli 2012.Randomised tswj kev sim hauv cov neeg uas muaj cystic fibrosis nrog pulmonary exacerbation nyob rau hauv uas cov kev kho mob nrog inhaled tshuaj tua kab mob yog muab piv rau cov placebo, standard kev kho mob los yog lwm yam inhaled tshuaj tua kab mob nyob rau nruab nrab ntawm ib thiab plaub lub lis piam. xaiv cov kev sim uas tsim nyog, ntsuas qhov kev pheej hmoo ntawm kev tsis ncaj ncees hauv txhua qhov kev sim thiab muab cov ntaub ntawv rho tawm.Cov kws sau ntawv ntawm cov kev sim uas suav nrog tau hu rau cov ntaub ntawv ntxiv. Rau qhov kev sim nrog 208 tus neeg koom tau suav nrog hauv kev tshuaj xyuas.Cov kev sim tau muaj ntau yam hauv kev tsim thiab kev cuam tshuam (txawm li cas los xij, tag nrho cov kev sim suav nrog piv rau kev nqus nqus thiab cov tshuaj tua kab mob hauv cov hlab ntsha).Kev pheej hmoo ntawm kev tsis ncaj ncees yog qhov nyuaj los ntsuas hauv ntau qhov kev sim siab.Cov txiaj ntsig tsis tau tshaj tawm tag nrho thiab tsuas yog cov ntaub ntawv txwv tsuas yog muaj rau kev tshuaj xyuas.Plaub qhov kev sim tau tshaj tawm qee qhov txiaj ntsig ntawm kev yuam lub ntim ntim ntawm ib thib ob thiab pom tsis muaj qhov sib txawv ntawm qhov nqus tau cov tshuaj tua kab mob thiab kev cuam tshuam tus tub sib piv.Hauv ob qhov kev sim no siv 300 mg ntawm qhov nqus tau tobramycin, qhov kev hloov pauv ntawm qhov yuam kev tas mus li ntawm ib thib ob yog zoo ib yam li tobramycin hauv cov hlab ntsha;thiab nyob rau hauv ib qho kev sim lub sij hawm kom txog rau thaum lub tom ntej exacerbation tsis txawv.Tsis muaj qhov cuam tshuam tseem ceeb tau raug tshaj tawm.Muaj cov pov thawj qib siab me me los txiav txim qhov ua tau zoo ntawm cov tshuaj tua kab mob rau kev kho mob pulmonary exacerbations hauv cov neeg mob cystic fibrosis.Cov kev sim uas suav nrog tsis muaj zog txaus kom ua tiav lawv cov hom phiaj.Yog li ntawd, peb tsis tuaj yeem ua pov thawj tias ib qho kev kho mob zoo dua rau lwm qhov lossis tsis tau.Kev tshawb fawb ntxiv yog xav tau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau ua rau cov kab mob hauv lub cev yuav tsum siv cov tshuaj tobramycin.