Cov khoom

Galactosidase yog hais txog ib chav kawm ntawm cov enzymes uas hydrolyze cov khoom uas muaj galactosidic bonds, xws li lactose (lactose yog ib tug disaccharide tsim los ntawm lub cev qhuav dej condensation ntawm ib molecule ntawm qabzib thiab ib molecule ntawm galactose).Feem ntau muab faib ua α-galactosidase thiab β-galactosidase.α-Galactosidase catalyzes hydrolysis ntawm α-galactosidase daim ntawv cog lus, uas tuaj yeem hloov thiab decompose cov khoom noj khoom haus α-galactosides hauv cov khoom noj thiab cov kua txiv hmab txiv ntoo, thiab txhim kho lawv cov khoom noj khoom haus.Tsis tas li ntawd, cov enzyme kuj muaj qee yam kev siv hauv kev lag luam tshuaj, thickener ua thiab ntawv lag luam.β-Galactosidase tsis yog tsuas yog siv ntau dua thiab dav hauv kev lag luam khoom noj, tab sis kuj tseem ua lub luag haujlwm tseem ceeb hauv kev lag luam biotechnology xws li genetic engineering, enzyme engineering, protein engineering, thiab lwm yam, thiab tau pib siv dav hauv tshuaj. thiab lwm yam teb.

α-galactosidase (α-galactosidase, α-gal, EC 3.2.1.22) yog ib qho exoglycosidase uas catalyzes hydrolysis ntawm α-galactosidic bonds, thiab tseem hu ua melibiase vim nws tuaj yeem decompose melibiose, uas catalyzes hydrolysis ntawm α-galactosidase. daim ntawv cog lus.Cov yam ntxwv no ua rau nws muaj txiaj ntsig zoo rau kev txhim kho thiab tshem tawm cov tshuaj tiv thaiv kab mob hauv cov khoom noj thiab cov kua txiv hmab txiv ntoo.Tsis tas li ntawd, nws tuaj yeem paub B → O cov ntshav hloov pauv hauv kev kho mob, npaj hom ntshav thoob ntiaj teb, thiab tseem ua lub luag haujlwm tseem ceeb hauv kev kho enzyme hloov pauv ntawm tus kab mob Fabry.Alpha-galactosidase tseem tuaj yeem ua rau cov polysaccharides complex, glycoproteins thiab sphingolipids uas muaj alpha-galactosidic bonds.Qee cov α-galactosidase enzymes kuj muaj cov nyhuv ntawm transgalactosylation thaum lub substrate concentration yog heev enriched, uas yuav siv tau rau cov synthesis ntawm oligosaccharides thiab kev npaj ntawm cyclodextrin derivatives.Kev txhim kho ntawm neutrophil lossis pH-ruaj khov α-galactosidase thiab kev tshawb nrhiav cov kab mob lossis cov nroj tsuag nrog cov enzyme siab ntau tau dhau los ua qhov kev tshawb fawb hotspot nyob rau hauv xyoo tas los.Ntau lub thermostable α-galactosidases kuj tau maj mam nyiam cov kws tshawb fawb thoob plaws vim lawv cov khoom tshwj xeeb, cia siab tias yuav siv lawv cov thermostability los ua lub luag haujlwm ntau dua hauv cov ntawv thov kev lag luam, nrog rau kev qhia dav dav hauv kev tshawb fawb thiab thev naus laus zis thiab tshuaj.thov kev cia siab.