Iodoacetamide Cas: 144-48-9 98% Dawb rau daj khoom
| Catalog Number | xwm 90247 |
| Khoom npe | Iodoacetamide |
| CAS | 144-48-9 : kuv |
| Molecular Formula | C2H4 NPO |
| Molecular Luj | 184.96 ib |
| Cov ntaub ntawv khaws cia | Ambient |
| Harmonized tariff Code | 29241900 ib |
Khoom Specification
| Poob rau ziab | <1% |
| Assay | ≥98% |
| Nitrogen | 7.2 - 7.8% |
| Qhov tshwm sim | Dawb rau daj khov |
| Solubility hauv methanol | Yuav luag pob tshab |
| Elemental Analysis Carbon | 12.5 - 13.2% |
α-Iodoacetamide yog ib qho chaw siv los ua electrophile rau covalent hloov kho ntawm nucleophilic residues ntawm cov proteins (cysteine, methionine, histidine).Thaum hloov cov active-site residues ntawm cysteine proteases, α-Iodoacetamide ua raws li ib tug irreversible inhibitor ntawm cov enzymes.
Kev Siv: Nws tuaj yeem siv los ua tus protease inhibitor CH2ICONH2.Zoo li iodoacetic acid, nws muaj peev xwm irreversibly inhibit SH enzymes los ntawm cov nram qab no cov tshuaj tiv thaiv.R-SH+ICH2CONH2 →RS-CH2CONH2+HI
Siv: Alkylation reagents rau histidine thiab cysteine hauv proteomics, rau peptide sequencing thiab enzyme inhibitors.Kuj tseem siv rau hauv cov organic synthesis.
