Cov khoom

Lub hom phiaj ntawm txoj kev tshawb fawb no yog los sib piv qhov ua tau zoo ntawm valproate piv rau haloperidol hauv kev txo qis kev ntxhov siab hauv cov neeg mob cuam tshuam hauv chav kho mob xwm txheej ceev.Peb tau muab 80 tus neeg mob mob hnyav kom tau txais cov tshuaj sodium valproate (20 mg / kg) lossis intramuscular haloperidol (5 mg / 1 ml).Kev ntxhov siab tau ntsuas ntawm lub hauv paus thiab 30 feeb tom qab thawj zaug txhaj tshuaj siv Agitation-Calmness Evaluation Scale (ACES), Qhov Zoo thiab Qhov Ncauj Mob Nplai-Excited Component subscale, thiab Agitated Behavior Scale.Rau 80 tus neeg mob kho nrog sodium valproate, qhov nruab nrab ± SD koob yog 1541.5 ± 286 mg (ntau 940-2400).Qhov nruab nrab postintervention ACES cov qhab nia ntawm lub hauv paus mus rau 30 min tom qab txhaj tshuaj yog 4.73 (SD = 1.93) rau pawg valproate thiab 5.45 (SD = 2.09) rau pawg haloperidol (P = 0.028).Tsis muaj qhov sib txawv tseem ceeb tau pom nyob rau hauv cov ntsiab lus ntawm qhov kev hloov pauv nruab nrab 30 feeb tom qab kev cuam tshuam rau ob qhov kev ntxhov siab ntxiv.Feem ntau ntawm cov neeg mob hauv pawg haloperidol tau ntsib kev mob siab rau (36.2%, P < 0.001) thiab cov tsos mob extrapyramidal (8.7%, P = 0.007) piv nrog valproate pawg (2.5% rau kev mob siab rau, tsis muaj tus neeg mob rau cov tsos mob extrapyramidal).Cov kev tshawb pom pom tau hais tias nyob rau hauv kev soj ntsuam kev teeb tsa ntawm kev puas siab puas ntsws thaum muaj xwm txheej ceev, valproate intravenous zoo li haloperidol hauv kev txo qis kev ntxhov siab, nrog rau kev nyab xeeb zoo dua.