5-Methyluridine CAS: 1463-10-1 99% Dawb hmoov
Catalog Number | xwm 90567 |
Khoom npe | 5-Methyluridine |
CAS | 1463-10-1 : kuv |
Molecular Formula | C10H14N2O6 |
Molecular Luj | 258.228 ib |
Cov ntaub ntawv khaws cia | 2 txog 8 ° C |
Harmonized tariff Code | 293499090 ib |
Khoom Specification
Qhov tshwm sim | Dawb hmoov |
Assay | 99% |
tRNA yog qhov hloov kho siab tshaj plaws ntawm RNA hom, thiab kev hloov kho muaj nyob hauv tRNAs los ntawm txhua yam kab mob uas tau kuaj xyuas.Txawm hais tias lawv cov qauv tshuaj sib txawv loj heev thiab lawv muaj nyob hauv cov tRNA sib txawv, tshwm sim nyob rau hauv ntau qhov chaw hauv tRNA, txoj hauv kev biosynthetic ntawm feem ntau ntawm tRNA hloov kho muaj xws li cov kauj ruam methylation.Cov kev tshawb pom tsis ntev los no tau qhia txog qhov nyuaj uas tsis tau pom dua hauv cov qauv hloov kho ntawm tRNA, lawv cov kev cai thiab kev ua haujlwm, qhia tias txhua qhov hloov pauv nucleoside hauv tRNA yuav muaj nws tus kheej tshwj xeeb.Txawm li cas los xij, hauv cov nroj tsuag, peb txoj kev paub txog lub luag haujlwm ntawm kev hloov kho tRNA tus kheej thiab lawv yuav tswj hwm li cas yog qhov tsawg heev.Hauv kev tshuaj ntsuam caj ces tsim los txheeb xyuas cov xwm txheej tswj cov kab mob tiv thaiv thiab ua kom muaj kev tiv thaiv hauv Arabidopsis, peb tau txheeb xyuas SUPPRESSOR OF CSB3 9 (SCS9).Peb cov txiaj ntsig tau nthuav tawm SCS9 encodes ib qho tRNA methyltransferase uas kho cov 2'-O-ribose methylation ntawm xaiv tRNA hom hauv antico don loop.Cov kev hloov kho SCS9-mediated tRNA no txhim kho thaum lub sijhawm kis kab mob nrog cov kab mob Pseudomonas syringae DC3000, thiab tsis muaj kev hloov kho tRNA, raws li tau pom hauv scs9 mutants, ua rau muaj kev cuam tshuam loj ntawm cov nroj tsuag tiv thaiv tib yam kab mob yam tsis muaj kev cuam tshuam rau salicylic acid (SA) signaling. txoj kev uas tswj cov nroj tsuag tiv thaiv kab mob.Peb cov txiaj ntsig tau txhawb nqa tus qauv uas muab qhov tseem ceeb rau kev tswj hwm ntawm qee qhov kev hloov kho tRNA rau kev txhim kho lub cev tiv thaiv kab mob zoo hauv Arabidopsis, thiab yog li nthuav tawm cov repertoire ntawm molecular Cheebtsam tseem ceeb rau kev tiv thaiv kab mob zoo.