4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-ib CAS: 951-77-9
| Catalog Number: | xwm 90580 |
| Cas: | 951-77-9 : kuv |
| Molecular Formula: | C9H13N3O4 |
| Molecular Luj: | 227.22 Nws |
| Muaj: | Hauv Tshuag |
| Nqe: | |
| Prepack: | 1g USD10 |
| Ntim Pob: | Thov Quote |
Khoom Specification
| Qhov tshwm sim | Dawb crystalline hmoov |
| Assay | 99% |
| Melting Point | 196 ° C - 200 ° C |
Thymidine phosphorylase (TP, EC 2.4.2.4) tau lees paub cov qauv ntawm cov substrate nrog cov ntsiab lus siab, ntawm ob qho tib si hauv paus thiab ribosyl moieties.Kev hloov pauv ntawm 3'-OH ntawm thymidine tau cuam tshuam nws txoj haujlwm catalytic nrog TP.Kev hloov pauv ntawm pyrimidine nucleosides nrog kev hloov pauv hauv paus moieties rau qhov sib thooj 1-phosphate daim ntawv tsis zoo.Cov kev tawm hauv pab pawg tau txo qis nrog kev nce hauv aromaticity ntawm pyrimidine puag moiety, vim muaj kev nyuaj siab ntxiv hauv polarizing lub hauv paus los ntawm cov amino acids hauv zos mus rau qhov chaw nquag.Kev hloov ntawm 3 ' thiab 5 ' cov pab pawg ua haujlwm tau txo qis cov tshuaj tiv thaiv thiab qhov feem pua ntawm kev hloov pauv nrog TP.Hauv particular, ribosyl 3 'hydroxyl pawg yog qhov tseem ceeb rau kev sib txuas ntawm cov substrate los ntawm enzyme.Qhov kev ntsuas kinetic kom meej meej pom qhov siab K (m) thiab qis V (max) qhov tseem ceeb ntawm kev hloov 3 'hydroxyl pawg nrog hydrogen.
