Cov khoom

Vancomycin hydrochloride yog glycopeptide tshuaj tua kab mob thiab yog hydrochloride ntsev ntawm vancomycin.Nws yog dawb los yog dawb zoo li crystalline hmoov nyob rau hauv chav tsev kub.Nws cov txheej txheem ntawm kev ua yog tias nws tuaj yeem khi nrog kev sib raug zoo siab rau poly-terminus alanyl-alanine ntawm precursor peptide nyob rau ntawm phab ntsa ntawm tes ntawm cov kab mob rhiab heev, thaiv cov biosynthesis ntawm peptide glycan polymer tsim cov kab mob ntawm phab ntsa, thiab yog li. ua rau muaj qhov tsis xws ntawm cov phab ntsa ntawm tes thiab ua rau cov kab mob tua kab mob ntxiv.Tsis tas li ntawd, nws tseem tuaj yeem hloov pauv permeability ntawm cov kab mob cell membrane, thiab xaiv inhibiting RNA synthesis.Cov yam ntxwv ntawm vancomycin hydrochloride yog nws cov kab mob muaj zog tiv thaiv kab mob Gram-zoo xws li Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, thiab streptococcus pneumoniae.Nws kuj muaj qee yam tshuaj tiv thaiv kab mob ntawm Streptococci anaerobius, Clostridium difficile, Bacillus anthracis, Actinomycetes, Corynebacterium diphtheria, Neisseria gonorrhoeae, Streptococcus viridans, Streptococcus bovis, thiab Streptococcus faecalis.Txawm li cas los xij, rau feem ntau cov kab mob Gram-negative, Mycobacterium, Rickettsia genus, Chlamydia lossis fungi, nws tsis siv.Nws yog siv rau kev kho mob ntawm tus kab mob tshwm sim los ntawm methicillin-resistant Staphylococcus aureus thiab lwm yam kab mob: sepsis, endocarditis, osteomyelitis, mob caj dab, kub hnyiab raug mob, phais raug mob thiab lwm yam superficial ob sab kab mob, mob ntsws, ntsws abscess, empyema, peritonitis, meningitis, pseudomembranous colitis, thiab kab mob ntawm daim tawv nqaij thiab cov nqaij mos.Nws yog thawj qhov kev xaiv rau cov neeg mob uas tsis haum rau penicillin thiab raug kev txom nyem los ntawm enterococcal endocarditis thiab Corynebacterium (chav diphtheria sp) endocarditis.