Thiamphenicol Cas: 15318-45-3
Catalog Number | xwm 92378 |
Khoom npe | Thiamphenicol |
CAS | 15318-45-3 |
Molecular Formula | C12H15Cl2NO5S |
Molecular Luj | 356.22 ib |
Cov ntaub ntawv khaws cia | Ambient |
Harmonized tariff Code | 29414000 ib |
Khoom Specification
Qhov tshwm sim | Dawb crystalline hmoov |
Assay | 99% min |
Melting Point | 163 ° C - 167 ° C |
Cov hlau hnyav | ≤10ppm |
Poob rau ziab | ≤ 1.0% |
Kev sib hloov kho qhov muag tshwj xeeb | -21° - 24° |
Chloride | ≤0.02% |
Thiamphenicol yog broad-spectrum tshuaj tua kab mob chloramphenicol, uas muaj txiaj ntsig zoo rau cov kab mob gram-tsis zoo dua li cov kab mob gram-zoo.Nyob rau hauv chav tsev kub, nws yog ib tug dawb mus rau off-dawb crystalline hmoov los yog siv lead ua, uas yuav tsum tau sai thiab kiag li nqus los ntawm lub qhov ncauj kev tswj, raws li zoo raws li nws yog excreted mas nyob rau hauv cov qauv ntawm cov zis rau cov metabolism.Nws yog siv rau kev kho mob ntawm kev ua pa, urinary ib ntsuj av, daim siab thiab gallbladder, typhoid thiab lwm yam kev phais plab hnyuv, gynecology thiab ENT kab mob.Tshwj xeeb tshaj yog nyob rau hauv cov kab mob me me nws yog qhov zoo dua.Nws muaj cov qauv tshuaj zoo sib xws nrog chloramphenicol.Nws cov methyl sulfone hloov cov nitro ntawm chloramphenicol, uas txo nws cov toxicity, thiab nyob rau hauv vivo nws antibacterial kev ua si yog 2.5-5 npaug zog dua chloramphenicol.Rau cov kab mob gram-zoo, xws li streptococcus pneumoniae thiab hemolytic streptococcus, nws muaj cov kab mob muaj zog heev, thaum cov kab mob gram-tsis zoo, xws li Neisseria gonorrhoeae, meningococcus, ntsws Bacteroides, E. coli, Vibrio cholerae, Shigella thiab inacill. nws kuj muaj zog antibacterial nyhuv.Rau cov kab mob anaerobic, Rickettsia thiab amoeba, nws muaj cov kab mob tua kab mob hauv qee qhov.Nws muaj tib yam tshuaj tiv thaiv kab mob nrog chloramphenicol, uas feem ntau inhibits cov synthesis ntawm cov kab mob protein.Cov tshuaj no yog nqus sai sai los ntawm kev tswj qhov ncauj, uas ncav cuag cov ntshav siab tshaj plaws hauv ob teev.Nws ib nrab-lub neej yog 5 teev, uas yog ntev tshaj li chloramphenicol.Cov kab mob no muaj cov kab mob ua tiav rau nws thiab chloramphenicol, thaum cov kab mob muaj qee qhov cuam tshuam rau nws thiab tetracycline.
Thiamphenicol kuj muaj zog tiv thaiv kab mob, uas yog ib qho tshuaj tiv thaiv kab mob zoo heev.Nws cov txheej txheem ntawm kev ua tau txawv txawv nrog rau lwm cov tshuaj tiv thaiv kab mob.Cov nyhuv immunosuppressive yog ob peb zaug ntau dua li chloramphenicol.Nws tuaj yeem ua tau raws li cov txiaj ntsig zoo rau kev hloov pauv cov tshuaj tiv thaiv thiab kev phais allogeneic hloov pauv.