Thiabendazole Cas: 148-79-8
| Catalog Number | xwm 92377 |
| Khoom npe | Thiabendazole |
| CAS | 148-79-8 ib |
| Molecular Formula | C10H7N3S |
| Molecular Luj | 201.25 Nws |
| Cov ntaub ntawv khaws cia | Ambient |
| Harmonized tariff Code | 29414000 ib |
Khoom Specification
| Qhov tshwm sim | dawb crystal hmoov |
| Assay | 99% min |
| Melting Point | 296-303 ° C |
| Dej | <0.5% |
Thiabendazole yog ib tug benzimidazole derivative qhia raws li ib tug veterinary tshuaj thaum lub sij hawm 1960s thiab tom qab ntawd raws li ib tug tib neeg anthelminthic tshuaj.Nws muaj qhov dav spectrum anthelminthic kev ua tau zoo tiv thaiv ntau hom kab mob nematode.Nws yog ob qho tib si ovicidal thiab larvicidal.Nws kuj tseem muaj txiaj ntsig zoo tiv thaiv ntau yam saprophytic thiab pathogenic fungi hauv vitro thiab kuj tau pom tias muaj kev tiv thaiv kab mob, antipyretic thiab analgesic zog hauv cov tsiaj kuaj[1].Clinically, nws yog feem ntau siv tawm tsam Strongyloides stercoralis thiab cutaneous larva migrans.
Lub mechanism ntawm kev txiav txim yog tsis meej to taub.Nws tau pom tias inhibit mitochondrial fumurate reductase, uas yog tshwj xeeb rau helminths [2].Thiabendazole kuj tseem tuaj yeem cuam tshuam cov kab mob parasite microtubules, los ntawm cov txheej txheem zoo ib yam li tau piav qhia rau mebendazole (saib Mebendazole).
