Tazobactam Cas: 89786-04-9
| Catalog Number | xwm 92373 |
| Khoom npe | Tazobactam |
| CAS | 89786-04-9 |
| Molecular Formula | C10H12N4O5S |
| Molecular Luj | 300.29 Nws |
| Cov ntaub ntawv khaws cia | -15 rau -20 ° C |
| Harmonized tariff Code | 29419000 ib |
Khoom Specification
| Qhov tshwm sim | Dawb mus rau dawb hmoov |
| Assay | 99% min |
| Dej | <0.5% |
| Kev sib hloov tshwj xeeb | +127 txog +139 |
| Cov hlau hnyav | <20 ppm |
| Residue ntawm Ignition | <0.1% |
| Tag nrho cov impurities | <1.0% |
Tazobactam yog penicillanic acid sulfone uas zoo ib yam li cov lus qhia rau sulbactam.Nws yog ib tug muaj zog β-lactamaseinhibitor ntau dua sulbactam thiab muaj ib tug me ntsis spectrumof kev ua si tshaj clavulanic acid.Nws muaj zog heev antibacterialactivity.Tazobactam yog muaj nyob rau hauv koob tshuaj, injectablecombinations nrog piperacillin, ib tug broad-spectrum penicillin uas muaj ib tug 8: 1 piv ntawm piperacillin sodium rau tazobactamsodium los ntawm qhov hnyav thiab ua lag luam raws li lub npe lag luam Zosyn.Cov tshuaj pharmacokinetics ntawm ob cov tshuaj no zoo sib xws.Ob leeg muaj lub neej luv luv (t1/2 ~ 1 teev), muaj cov protein tsawg tsawg, muaj cov metabolism hauv me me, thiab raug tso tawm cov ntaub ntawv tsis muaj zog hauv cov zis hauv siab.
Pom zoo indications rau lub piperacillin-tazobactamcombination muaj xws li kev kho mob ntawm appendicitis, postpartumendometritis, thiab pelvic inflammatory kab mob tshwm sim los ntawm beta-lactamase-producing E. coli thiab Bacteroides spp., daim tawv nqaij thiab daim tawv nqaij qauv kab mob tshwm sim los ntawm β-lactamase-producingS.aureus, thiab mob ntsws los ntawm β-lactamase-producingstrains ntawm H. influenzae.
