Pyridoxal-5′-phosphate monohydrate CAS: 41468-25-1 99% Tawm-dawb rau lub teeb daj hmoov
| Catalog Number | xwm 90390 |
| Khoom npe | Pyridoxal-5'-phosphate monohydrate |
| CAS | 41468-25-1 |
| Molecular Formula | C8H10NO6P · H2O |
| Molecular Luj | 265.16 Nws |
| Cov ntaub ntawv khaws cia | 2 txog 8 ° C |
| Harmonized tariff Code | 29362500 ib |
Khoom Specification
| Cov hlau hnyav | 20 ppm max |
| Tag nrho cov phaj suav | 1000 cfu/g max |
| E. Coli | Tsis zoo |
| Salmonella | Tsis zoo |
| Poob rau ziab | 10.0% max |
| Staphylococcus aureus | Tsis zoo |
| Assay | 99% |
| Qhov tshwm sim | Tawm-dawb mus rau lub teeb daj hmoov |
| Poov & Pwm suav | 100 cfu/g max |
| Hnub tsim khoom | TBC |
| Coliform | Tsis zoo |
| Pyridoxine (HPLC) | 0.01% max |
| PH (0.25% ag Solution) | 2.6-3.0 Nws |
Kev kho kom zoo ntawm myelin nyob rau hauv cov neeg laus CNS yuav tsum muaj kev tsim cov myelin proteins uas muaj zog thiab raws sijhawm los tsim cov myelin sheaths tshiab.Txawm li cas los xij, cov txheej txheem tswj hwm thiab cov txheej txheem molecular complex ntawm myelin regeneration, txawm li cas los xij, tseem tsis to taub.Ntawm no, peb tshawb xyuas lub luag haujlwm ntawm ERK MAP kinase signaling hauv cov txheej txheem no.Cov xwm txheej tshem tawm ntawm Erk2 los ntawm cov hlwb ntawm cov kab mob oligodendrocyte ua rau ncua sijhawm remyelination tom qab demyelinating raug mob rau tus neeg laus nas corpus callosum.Kev kho qeeb tau tshwm sim los ntawm qhov tsis txaus ntseeg hauv kev txhais lus ntawm cov protein myelin loj, MBP.Thaum tsis muaj ERK2, ua kom cov ribosomal protein S6 kinase (p70S6K) thiab nws lub hom phiaj nqes hav, ribosomal protein S6 (S6RP), tau ua tsis taus nyob rau lub sij hawm tseem ceeb thaum premyelinating oligodendrocytes tau hloov mus rau cov laus laus muaj peev xwm tsim cov myelin sheaths tshiab.Yog li, peb tau piav qhia txog qhov tseem ceeb ntawm kev sib txuas ntawm ERK MAP kinase signaling cascade thiab translational machinery tshwj xeeb hauv remyelinating oligodendrocytes hauv vivo.Cov txiaj ntsig no qhia txog lub luag haujlwm tseem ceeb rau ERK2 hauv kev tswj hwm kev txhais lus ntawm MBP, cov protein myelin uas zoo li tseem ceeb rau kev ua kom lub sijhawm tsim cov myelin sheaths tshiab tom qab demyelinating raug mob hauv cov neeg laus CNS.
