Lipase los ntawm porcine pancreas CAS: 9001-62-1 Xim av rau beige hmoov
| Catalog Number | xwm 90387 |
| Khoom npe | Lipase los ntawm porcine pancreas |
| CAS | 9001-62-1 |
| Molecular Formula | N/A |
| Molecular Luj | N/A |
| Cov ntaub ntawv khaws cia | 2 txog 8 ° C |
| Harmonized tariff Code | 3 50790 |
Khoom Specification
| Tshauv | <12% |
| AS | <2 mg/kg |
| Pb | <2 mg/kg |
| Cov ntsiab lus dej | <8% |
| Assay | 99% |
| Kev ua enzyme | > 30000u/g |
| Qhov tshwm sim | Brown rau beige hmoov |
| Coliform Group | <30MPH/100g |
| Kev tshawb fawb siv nkaus xwb, tsis yog siv rau tib neeg | kev tshawb fawb siv xwb, tsis yog rau tib neeg siv |
Kev hloov pauv ntawm triglyceride (TG) cov metabolism hauv vascular du leeg hlwb (SMC) yuav muaj feem cuam tshuam nrog qee yam phenotype, tab sis qhov no tsis tau piav qhia.Adipose triglyceride lipase (ATGL) ua haujlwm loj TG catalytic kev ua haujlwm hauv ob qho tib si adipotic thiab non-adipotic hlwb.Hauv txoj kev tshawb no, peb cais SMC los ntawm ATGL-tsis muaj nas (ATGL(-/-)mSMC).ATGL(-/-)mSMC tau pom qhov tshwm sim ntawm TG txuam nrog qis mitogenic cov lus teb thiab cov leeg nqaij leeg (SMA) qhia piv rau ATGL (+/+)mSMC.Feem pua ntawm senescence-associated _-galactosidase zoo hlwb kuj tau nce hauv ATGL(-/-)mSMC.Real-time PCR ua raws li kev tshuaj ntsuam nrog tsom DNA array tsom xam qhia txog kev qhia txog glucokinase (1.7-fold), lipoprotein lipase (3.8-fold) thiab interleukin-6 (3.7-fold) thiab txo qis kev qhia ntawm vascular endothelial kev loj hlob. factor-A (0.2-fold), type I collagen (0.5-fold), thiab transforming growth factor-_ (0.4-fold) hauv ATGL(-/-)mSMC piv rau ATGL(+/+)mSMC.Tom ntej no, ectopic gene hloov ntawm tib neeg ATGL tau sim siv doxycycline (Dox)-regulatable myc-DDK-tagged adenovirus vector (AdvATGL).AdvATGL tus kab mob ua rau txo qis ntawm TG txuam nrog cov lus teb mitogenic siab thiab SMA qhia, thiab txo qis hauv cov xov tooj ntawm tes hauv ATGL (-/-) mSMC.Ntxiv mus, deviated gene qhia qauv hauv ATGL(-/-)mSMC tau raug kho.Peb cov ntaub ntawv qhia tias ATGL(-/-)mSMC muaj qhov txawv phenotype uas yuav cuam tshuam rau vascular pathogenesis.Plasticity ntawm SMC phenotypes cuam tshuam rau lipid metabolism tuaj yeem yog lub hom phiaj kho.
