Cov khoom

7-Hydroxygranisetron yog ib qho tshuaj uas ua haujlwm hauv cov tshuaj.Nws belongs rau ib chav kawm ntawm cov tshuaj hu ua xaiv serotonin 5-HT3 receptor antagonists.Cov tshuaj no yog ib qho metabolite ntawm granisetron, ib qho tshuaj antiemetic feem ntau.Lub hom phiaj tseem ceeb ntawm 7-Hydroxygranisetron yog txhawm rau tiv thaiv thiab kho xeev siab thiab ntuav, tshwj xeeb tshaj yog cov kev cuam tshuam nrog kev kho mob lossis kev phais.Chemotherapy-induced xeev siab thiab ntuav (CINV) yog ib qho kev txhawj xeeb tseem ceeb rau cov neeg mob qog noj ntshav uas tab tom kho.Cov kev mob tshwm sim no tuaj yeem cuam tshuam rau tus neeg mob lub neej zoo thiab tuaj yeem ua rau muaj kev cuam tshuam kev kho mob.7-Hydroxygranisetron ua haujlwm los ntawm kev thaiv cov serotonin receptors tshwj xeeb hauv lub hauv paus paj hlwb, tshwj xeeb tshaj yog cov nyob hauv thaj chaw chemoreceptor trigger tsam thiab ntuav chaw.Los ntawm kev ua li ntawd, nws yuav pab txo qis cov teeb meem uas ua rau xeev siab thiab ntuav, muab kev pab rau cov neeg mob.Ntxiv rau nws siv rau CINV, 7-Hydroxygranisetron kuj tau pom cov lus cog tseg hauv kev tswj cov xeev siab thiab ntuav (PONV).Tom qab cov txheej txheem phais, cov neeg mob feem ntau raug kev xeev siab thiab ntuav vim muaj kev cuam tshuam ntawm kev siv tshuaj loog thiab lwm yam.7-Hydroxygranisetron pab tiv thaiv thiab tswj cov tsos mob no, ua rau cov neeg mob rov zoo li qub.Thaum siv tshuaj, 7-Hydroxygranisetron feem ntau yog muab tso rau hauv cov hlab ntsha lossis qhov ncauj, nyob ntawm tus neeg mob tus mob thiab kev kho mob.Qhov ntau npaum li cas yuav txawv raws li cov xwm txheej xws li tus neeg qhov hnyav, cov txheej txheem tshwj xeeb lossis kev kho mob, thiab qhov hnyav ntawm cov tsos mob.Nws yog ib qho tseem ceeb uas yuav tsum tau ua raws li cov tshuaj thiab cov lus qhia muab los ntawm cov kws kho mob kom ntseeg tau tias kev ua tau zoo thiab tsis txhob muaj kev phiv tshwm sim. Zoo li ntau cov tshuaj, 7-Hydroxygranisetron tuaj yeem muaj cov kev mob tshwm sim.Cov no yuav muaj xws li mob taub hau, cem quav, raws plab, kiv taub hau, thiab qaug zog.Muaj tsawg zaus, cov tib neeg yuav muaj kev tsis haum tshuaj los yog muaj kev phom sij loj dua.Nws yog ib qho tseem ceeb uas yuav tsum tau tshaj tawm txog cov tsos mob lossis kev cuam tshuam rau tus kws kho mob kom tsim nyog kev ntsuam xyuas thiab kev tswj hwm. Hauv kev xaus, 7-Hydroxygranisetron yog ib qho tshuaj siv los tiv thaiv thiab kho xeev siab thiab ntuav cuam tshuam nrog kev siv tshuaj khomob thiab kev phais.Los ntawm thaiv qee cov serotonin receptors hauv nruab nrab paj hlwb, nws pab txo cov tsos mob ntxhov siab hauv cov neeg mob qog noj ntshav thiab cov tib neeg rov zoo los ntawm kev phais.Txawm li cas los xij, zoo li txhua yam tshuaj, nws