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5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinone CAS: 545445-44-1
| Catalog Number | xwm 93344 |
| Khoom npe | 5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinone |
| CAS | 545445-44-1 |
| Molecular Formula | C20H25N3O3 |
| Molecular Luj | 355.43 ib |
| Cov ntaub ntawv khaws cia | Ambient |
Khoom Specification
| Qhov tshwm sim | Dawb hmoov |
| Assay | 99% min |
5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinone, tseem hu ua DMPHP, yog ib qho heterocyclic compound nrog ntau yam kev siv hauv tshuaj chemistry thiab tshuaj nrhiav pom.Ntawm no yog ib qho kev piav qhia ntawm nws cov kev siv nyob rau hauv hais txog 300 lo lus.DPHP paub txog nws lub peev xwm raws li ib tug muaj zog thiab xaiv inhibitor ntawm tej enzymes thiab receptors nyob rau hauv tib neeg lub cev.Ib qho ntawm nws cov kev siv tseem ceeb yog nyob rau hauv thaj tsam ntawm kinase inhibition.Kinases yog cov enzymes uas ua lub luag haujlwm tseem ceeb hauv cell signaling pathways thiab feem ntau cuam tshuam rau ntau yam kab mob, suav nrog mob qog noj ntshav.DPHP tau pom tias xaiv inhibit kinases tshwj xeeb, yog li cuam tshuam cov teeb liab tsis txaus ntseeg uas ua rau muaj kab mob.Qhov no ua rau nws yog ib tus neeg sib tw ua tau zoo rau kev txhim kho cov phiaj xwm kev kho mob rau ntau yam kab mob, suav nrog mob qog noj ntshav, o, thiab kab mob hauv lub paj hlwb. Tsis tas li ntawd, DPHP tau pom muaj peev xwm hauv thaj tsam ntawm kev tiv thaiv kab mob thiab kev tiv thaiv kab mob immunomodulatory.Kev mob yog ib qho kev teb ntawm lub cev rau kev kis kab mob lossis kev raug mob tab sis tuaj yeem ua mob ntev thiab ua rau ntau yam kab mob.DPHP tau pom tias muaj peev xwm los cuam tshuam qee txoj hauv kev tiv thaiv kab mob, txo qis kev tsim cov kab mob sib kis.Cov cuab yeej no ua rau nws muaj txiaj ntsig zoo hauv kev txhim kho cov tshuaj tiv thaiv kab mob, pab kho cov mob xws li mob caj dab rheumatoid, kab mob plab hnyuv, thiab mob hawb pob.DPHP kuj tau tshawb xyuas rau nws lub peev xwm los ua tshuaj tua kab mob lossis tshuaj tua kab mob. .Kev mob ntev yog ib qho teeb meem loj rau kev noj qab haus huv, thiab cov kev kho mob tam sim no feem ntau muaj kev txwv lossis tsis xav tau kev phiv.DPHP tau pom cov teebmeem analgesic hauv cov kev tshawb fawb preclinical, qhia nws lub peev xwm los ua ib qho kev kho tshiab rau kev tswj qhov mob.Los ntawm kev hloov kho cov receptors tshwj xeeb thiab cov tshuaj neurotransmitters koom nrog hauv kev hnov mob, DPHP tuaj yeem muab lwm txoj hauv kev rau kev tswj kev mob uas muaj feem cuam tshuam tsawg dua. Tsis tas li ntawd, DPHP tau qhia cov lus cog tseg hauv thaj chaw hauv nruab nrab lub paj hlwb (CNS).Neurological tej yam kev mob xws li Alzheimer's kab mob thiab Parkinson tus kab mob koom nrog complex mechanisms thiab dysregulation ntawm ntau yam receptors thiab enzymes nyob rau hauv lub hlwb.DPHP tau kawm txog nws lub peev xwm ua tus neeg saib xyuas neuroprotective thiab rau nws lub peev xwm los txhim kho kev txawj ntse.Los ntawm lub hom phiaj tshwj xeeb receptors thiab txoj hauv kev koom nrog hauv cov kab mob neurodegenerative, DPHP tuav cov lus cog tseg raws li kev kho mob rau cov kev nyuaj no. 1-piperidinyl) phenyl]-2 (1H)-pyridinone (DPHP) yog ib qho kev sib xyaw ua ke uas muaj peev xwm siv tau hauv kinase inhibition, kev ua haujlwm tiv thaiv kab mob, analgesia, thiab neuroprotection.Nws lub peev xwm los xaiv cov enzymes tshwj xeeb thiab cov receptors koom nrog hauv cov kab mob ua rau nws yog tus neeg sib tw txaus nyiam rau kev tshawb nrhiav tshuaj thiab kev kho mob.Kev tshawb fawb ntxiv thiab kev txhim kho tuaj yeem nthuav tawm kev siv ntxiv thiab ua kom zoo dua nws cov khoom rau cov lus qhia tshwj xeeb.
