Fluorescein 5-Isothiocyanate (isomer I) CAS: 3326-32-7
| Catalog Number | xwm 90514 |
| Khoom npe | Fluorescein 5-Isothiocyanate (isomer kuv) |
| CAS | 3326-32-7 |
| Molecular Formula | C21H11NO5S |
| Molecular Luj | 389.38 ib |
| Cov ntaub ntawv khaws cia | 2 txog 8 ° C |
| Harmonized tariff Code | 32129000 ib |
Khoom Specification
| Qhov tshwm sim | Lub teeb daj hmoov |
| Assay | 99% |
Ischemic stroke tau pom tias ua rau hypermetabolism ntawm cov piam thaj hauv ischemic penumbra.Kev sim thiab cov ntaub ntawv kho mob qhia tau hais tias infarct-related systemic hyperglycemia yog lub hom phiaj kho mob hauv mob stroke.Txawm li cas los xij, cov kev tshawb fawb soj ntsuam tsom rau kev tswj cov piam thaj hauv cov mob stroke tsis tau txhim kho cov txiaj ntsig zoo lossis txo cov neeg tuag.Yog li, kev tshawb fawb ntxiv ntawm cov piam thaj hauv cov metabolism hauv lub hlwb ischemic tau lav.Peb tau siv cov qauv nas ntawm cov hlab ntsha uas khaws cov khoom lag luam.Cov tsiaj tau txheeb xyuas los ntawm [2-(18)F]-2-fluoro-2-deoxy-d-glucose positron emission tomography lossis magnetic resonance imaging thaum 90-feeb occlusion ntawm nruab nrab cerebral hlab ntsha thiab thaum lub sij hawm 60 feeb tom qab reperfusion.Cov txiaj ntsig tau cuam tshuam nrog kev sib nqus resonance imaging ntawm cerebral ntshav khiav, diffusion ntawm dej, lactate tsim, thiab histological cov ntaub ntawv ntawm cell tuag thiab ntshav-brain barrier breakdown. -deoxy-d-glucose uptake hauv ischemic re gions succumbing rau infarction thiab hauv cheeb tsam peri-infarct.Magnetic resonance imaging qhia txog kev puas tsuaj ntawm cov ntshav ntws mus rau cov qib ischemic nyob rau hauv infarct thiab txo cov ntshav cerebral ntws hauv cheeb tsam peri-infarct.Sib nqus resonance spectroscopy qhia lactate hauv thaj av ischemic thiab tsis muaj lactate hauv thaj tsam peri-infarct.Cov tshuaj immunohistochemical tsom xam pom tias apoptosis thiab ntshav-hlwb lub teeb meem kev puas tsuaj nyob rau hauv lub infarct.Qhov nce ntawm [2-(18)F]-2-fluoro-2-deoxy-d-glucose hauv cerebral ischemia feem ntau yuav qhia txog hypermetabolism ntawm qabzib lub rooj sib tham nce zog. kev xav tau ntawm ischemic thiab hypoperfused hlwb cov ntaub so ntswg, thiab nws tshwm sim nyob rau hauv ob qho tib si anaerobic thiab aerobic tej yam kev mob ntsuas los ntawm lub zos lactate ntau lawm.Infarct-related systemic hyperglycemia tuaj yeem pab txhawb nqa cov piam thaj rau lub hlwb ischemic.Kev tswj glycemic los ntawm kev kho mob insulin tuaj yeem cuam tshuam tsis zoo rau cov txheej txheem no.
