Lub teeb ntsuab SF Cas: 5141-20-8 Sib sib zog nqus ntshav hmoov
| Catalog Number | xwm 90538 |
| Khoom npe | Lub teeb ntsuab SF |
| CAS | 5141-20-8 |
| Molecular Formula | C₃₇H₃₄N₂Na₂O₉S₃ |
| Molecular Luj | 792.86 ib |
| Cov ntaub ntawv khaws cia | -15 rau -20 ° C |
| Harmonized tariff Code | 32129000 ib |
Khoom Specification
| Qhov tshwm sim | Ntshav qab zib hmoov |
| Assay | 99% |
| Solubility | Soluble hauv dej kom muab cov tshuaj ntsuab ntshiab |
Txhawm rau soj ntsuam cov yam ntxwv ntawm qhov staining thiab kev nyab xeeb ntawm qhov muaj peev xwm tshiab dyes rau kev phais intraocular.Six dyes tau suav nrog hauv kev tshawb nrhiav: lub teeb ntsuab SF (LGSF) yellowish, E68, bromophenol xiav (BPB), Chicago xiav (CB), rhodamine 6G, rhodulinblau -basic 3 (RDB-B3).Tag nrho cov dyes tau yaj thiab diluted nyob rau hauv ib tug balanced saline saline tov.Lub teeb-absorbing zog ntawm txhua dye yog ntsuas ntawm ib tug concentration ntawm 0.05% ntawm 200 thiab 1000 nm.Cov yam ntxwv staining raug tshuaj xyuas los ntawm staining lens capsule cov ntaub so ntswg thiab epiretinal daim nyias nyias (ERMs), tshem tawm intraoperatively, nrog dye concentrations ntawm 1.0%, 0.5%, 0.2%, thiab 0.05%.Enucleated porcine ob lub qhov muag (lub sijhawm postmortem, 9 teev) kuj tau stained.Dye-related toxicity raug soj ntsuam los ntawm kev kuaj colorimetric (MTT) ntsuas qhov inhibition ntawm retinal pigment epithelium (RPE) cell proliferation (ARPE-19 thiab thawj tib neeg RPE hlwb, nqe 3-6).Cell viability kuj raug txheeb xyuas raws li ob-xim fluorescence cell-vability assay.Dyes raug tshawb xyuas nyob rau hauv qhov ntau ntawm 0.2% thiab 0.02%.Txhua cov dyes tshawb xyuas hauv qhov kev tshawb fawb no ua rau tib neeg lub lens capsules, tshem tawm intraoperatively;ERMs, tev tawm thaum phais macular pucker;thiab enucleated porcine ob lub qhov muag, nyob ntawm qhov concentration thov.Qhov ntev-wavelength absorption siab tshaj plaws ntawm cov dyes yog nyob rau hauv thaj tsam ntawm 527 mus rau 655 nm ntawm concentrations ntawm 0.05%.Rhodamine G6 thiab RDB-B3 tau pom qhov tsis zoo ntawm ARPE-19 cell proliferation ntawm qhov concentration ntawm 0.2% thiab raug tshem tawm los ntawm kev tshawb fawb ntxiv hauv thawj RPE hlwb.Cov plaub dyes ntxiv tau pom tias tsis muaj tshuaj lom rau ARPE-19 thiab thawj RPE cell proliferation ntawm qhov ntau ntawm 0.2% thiab 0.02%.Cell viability raug cuam tshuam los ntawm LGSF yellowish (0.2%) thiab CB (0.2% thiab 0.02%).Ob lub dyes (E68 thiab BPB) tsis pom muaj qhov cuam tshuam toxicity hauv vitro.Qhov kev ntsuam xyuas ntawm cov dyes rau kev siv intraocular zoo li yuav tsum tau ua.Nyob rau hauv txoj kev tshawb no plaub dyes tau txheeb xyuas nrog cov yam ntxwv zoo staining, nrog rau ob ntawm cov dyes tsis muaj tshuaj lom rau RPE hlwb hauv vitro.
