BETA-NADPH TETRA (CYCLOHEXYLAMMONIUM) Ntsev Cas: 100929-71-3
| Catalog Number | xwm 90431 |
| Khoom npe | BETA-NADPH TETRA (CYCLOHEXYLAMMONIUM) ntsev |
| CAS | 100929-71-3 |
| Molecular Formula | C21H30N7O17P3.4 [C6H13N] |
| Molecular Luj | 1142.11748 ib |
| Cov ntaub ntawv khaws cia | -20 ° C |
Khoom Specification
| Qhov tshwm sim | Dawb hmoov |
| Assay | 99% |
NADPH oxidases yog ib tsev neeg ntawm cov enzymes uas tsim cov pa oxygen reactive (ROS).Cov NOX1 (NADPH oxidase 1) thiab NOX2 oxidases yog qhov tseem ceeb ntawm ROS nyob rau hauv cov hlab ntsha phab ntsa hauv cov mob xws li kub siab, hypercholesterolemia, ntshav qab zib thiab kev laus, thiab yog li lawv yog cov tseem ceeb rau oxidative kev nyuaj siab, endothelial dysfunction thiab vascular o uas underlies. Kev kho mob ntawm cov hlab ntsha thiab atherogenesis.Hauv qhov Kev Ntsuam Xyuas no, peb ua ntej lub tswv yim uas piv rau kev siv cov tshuaj antioxidants, inhibiting NOX1 thiab NOX2 oxidases yog ib txoj hauv kev zoo tshaj rau kev tawm tsam oxidative kev nyuaj siab.Peb piav qhia luv luv txog qee qhov tshwm sim thiab tshwm sim putative NADPH oxidase inhibitors.Tsis tas li ntawd, peb hais txog lub luag haujlwm tseem ceeb ntawm NADPH oxidase kev tswj hwm subunit, p47phox, hauv kev ua haujlwm ntawm vascular NOX1 thiab NOX2 oxidases, thiab qhia txog yuav ua li cas kev nkag siab zoo ntawm nws cov kev sib cuam tshuam ntawm molecular yuav ua rau kev txhim kho cov tshuaj tshiab isoform-xaiv los tiv thaiv. los yog kho cov kab mob cardiova scular.
