(2S,3R)-2-Amino-3-hydroxybutanoic acid Cas: 72-19-5 99% Dawb crystalline hmoov
Catalog Number | xwm 90285 |
Khoom npe | (2S, 3R)-2-Amino-3-hydroxybutanoic acid |
CAS | 72-19-5 ib |
Molecular Formula | C4H9NO3 |
Molecular Luj | 119.11916 |
Cov ntaub ntawv khaws cia | Ambient |
Harmonized tariff Code | 29225 000 ib |
Khoom Specification
Assay | 99 - 101% |
Qhov tshwm sim | Dawb crystalline hmoov |
Kev sib hloov tshwj xeeb | -27.5 - 29.0 Nws |
Cov hlau hnyav | 10 ppm Max. |
AS | 10 ppm max |
pH | 5.2-6.5 |
SO4 | <0.020% |
Fe | 10 ppm max |
Poob rau ziab | <0.20% |
Residue ntawm Ignition | <0.10% |
Kev xa tawm | NLT 98% |
Cl | <0.02% |
Ammonium ntsev | <0.02% |
Serine / threonine protein phosphatase tau piav qhia nyob rau hauv ntau cov kab mob pathogenic raws li cov enzymes tseem ceeb koom nrog hauv phosphorylation-nyob ntawm cov teeb liab hloov txoj hauv kev thiab feem ntau cuam tshuam nrog kev ua phem ntawm cov kab mob no.Kev tshuaj xyuas ntawm Mycoplasma synoviae genome qhia pom muaj cov noob (prpC) encoding ib qho protein phosphatase ntawm cov protein phosphatase 2C (PP2C) subfamily.Ntawm no, peb qhia txog kev ua tiav biochemical characterization ntawm M. synoviae phosphatase (PrpC) thiab lub luag haujlwm tshwj xeeb ntawm cov hlau ions hauv cov qauv kev ua haujlwm ntawm cov enzyme no.PrpC amino acid sequence tsom xam qhia tias tag nrho cov residues koom nyob rau hauv lub dinuclear hlau chaw thiab lub putative thib peb hlau ion-coordinating residues, txuag nyob rau hauv PP2C phosphatase, muaj nyob rau hauv PrpC.PrpC yog monomeric protein muaj peev xwm dephosphorylate phospho-substrates nrog Mn (2+) ions 'dependence.Kev tsom xam thermal stability qhia tau hais tias cov enzyme stability ntawm qhov kub thiab txias thiab inf luence ntawm Mn (2+) ions hauv cov cuab yeej no.Mass spectrometry tsom xam pom tias peb cov hlau ions khi rau PrpC, ob qho tib si uas muaj qhov pom tseeb ntawm kev sib raug zoo siab tas li.Kev hloov pauv ntawm cov txheej txheem thib peb ntawm cov hlau sib koom ua ke, Asp122 thiab Arg164, qhia tias cov kev hloov pauv no tau nthuav tawm qhov tsis muaj zog ntawm manganese ions, thiab tias ob qho kev hloov pauv cuam tshuam rau PrpC phosphatase kev ua haujlwm.Raws li cov txiaj ntsig no, PrpC yog cov neeg koom nrog hlau-nyob rau hauv cov protein phosphatase nrog kev txhim kho kev ruaj ntseg hauv daim ntawv holo thiab nrog Asp122, tejzaum nws muaj feem cuam tshuam rau hauv qhov chaw thib peb hlau-khi, qhov tseem ceeb rau kev ua haujlwm catalytic.