Glutathione txo Cas: 70-18-8 98-101% Ntshiab thiab tsis muaj xim
| Catalog Number | xwm 90284 |
| Khoom npe | Glutathione txo |
| CAS | 70-18-8 ib |
| Molecular Formula | C10H17N3O6S |
| Molecular Luj | 307.32 Nws |
| Cov ntaub ntawv khaws cia | 2 txog 8 ° C |
| Harmonized tariff Code | 29 3098 ib |
Khoom Specification
| Assay | 98% - 101% |
| Qhov tshwm sim | Dawb crystalline hmoov |
| Qib | EP 7.0 |
| impurity A | <0.5% |
| Impurity B | <0.5% |
| Cov hlau hnyav | <10ppm |
| Cov kab mob endotoxin | <0.10EU/mg |
| Cov impurity C | <1.5% |
| Impurity D | <1.0% |
| Poob rau ziab | <0.5% |
| Solubility | Dawb soluble hauv dej, me ntsis soluble hauv ethanol thiab methylene chloride |
| Hlau | <10ppm |
| Chlorides | <200ppm |
| Qhov tshwm sim ntawm kev daws teeb meem | Ntshiab thiab tsis muaj xim |
| Kev sib hloov kho qhov muag tshwj xeeb | -15.5-17.5 Nws |
| Tag nrho cov impurities | <2.5% |
| Ammonium | <200ppm |
| Sulfated tshauv | <0.1% |
| Sulfates | <300ppm |
| Impurity E | <0.5% |
Kev hloov pauv cov protein tom qab, xws li tyrosine phosphorylation, tswj cov protein-protein interactions (PPIs) tseem ceeb rau kev ua cov teeb liab thiab cov phenotypes ntawm tes.Peb tau txuas ntxiv ib qho kev tsim cov poov xab ob-hybrid uas siv tib neeg cov protein kinases rau kev soj ntsuam ntawm phospho-tyrosine (pY)-nyob PPIs hauv kev sim ncaj qha, loj-loj mus kom ze.Peb tau txheeb xyuas 292 feem ntau cov tshiab pY-raws li PPIs uas tau pom tias muaj kev tshwj xeeb nrog rau kinases thiab interacting proteins thiab validated ib feem loj nyob rau hauv co-immunoprecipitation thwmsim los ntawm mammalian hlwb.Kwv yees li ib feem ntawm qhov kev sib cuam tshuam yog kho los ntawm kev paub cov kab sib txuas ua ke khi motifs thaum feem ntau ntawm pY-PPIs tau kho los ntawm lwm cov kab sib txuas los yog tswj hwm los ntawm lwm hom kev lees paub.Kev txheeb xyuas hauv lub network tau qhia tias pY-kev paub txog cov xwm txheej tau muab khi rau qhov kev sib txuas ntawm cov protein ntau uas mob siab rau kev taw qhia thiab txoj hauv kev loj hlob ntawm tes muaj feem xyuam rau kev mob qog noj ntshav.Siv cov kev txheeb xyuas kev sib txuas, cov protein ua kom tiav thiab cov ntawv nyeem phenotypic los ua tus yam ntxwv ntawm pY-dependent kev sib cuam tshuam ntawm TSPAN2 (tetraspanin 2) thiab GRB2 lossis PIK3R3 (p55γ), peb ua piv txwv muab pov thawj tias ob lub pY-dependent PPIs dictate cellular phenotypes.
