Tetracycline hydrochloride CAS: 64-75-5 99% Yellow crystalline hmoov
| Catalog Number | xwm 90366 |
| Khoom npe | Tetracycline hydrochloride |
| CAS | 64-75-5 ib |
| Molecular Formula | C22H24N2O8 · HCl |
| Molecular Luj | 480.90 ib |
| Cov ntaub ntawv khaws cia | -15 rau -20 ° C |
| Harmonized tariff Code | 29413 000 Nws |
Khoom Specification
| Xaus | Ua raws li BP2013, EP7, USP38 |
| Cov hlau hnyav | <0.005% |
| Ib leeg impurity | <0.1% |
| Kev txheeb xyuas | IR, UV, HPLC, TLC |
| pH | 1.8-2.8 Nws |
| Poob rau ziab | <2.0% |
| Residual kuab tshuaj | n-Butanol <3000ppm |
| Assay | PEB 2013/EP7 99% |
| Sulfated tshauv | <0.5% |
| Kev sib hloov kho qhov muag tshwj xeeb | -240 rau -255 ° |
| Muaj peev xwm | USP 38: > 900 ug/mg |
| Tag nrho cov impurities | <5% |
| Qhov tshwm sim | Yellow crystalline hmoov |
| 4-epianhydrotetracycline hmoov | <2% |
| Microbial txwv | Ua raws |
| 4-Epiteracycline | <3% |
| Anhydrotetracyoline | <0.5% |
| Chlortetracycline Hydrochloride | <0.5% |
| Residual Solvent | <100ppm |
Kev loj hlob ntawm cov tshuaj tiv thaiv kab mob tau raug xa mus rau ntau dhau thiab siv cov tshuaj tua kab mob tsis raug.Staphylococci yog ib feem ntawm cov nroj tsuag ib txwm muaj tab sis kuj yog cov kab mob uas muaj peev xwm ua tau los tiv thaiv ntau yam tshuaj tua kab mob.Kev tawm tsam hauv coagulase tsis zoo staphylococci (ConS) tau pom tias yuav hloov zuj zus vim qhov kev xaiv zoo tom qab kev kho tshuaj tua kab mob.Txoj kev tshawb no tau tshawb xyuas qhov muaj cuaj feem ntau siv cov tshuaj tua kab mob hauv tib neeg cov zis los ntawm cov neeg mob sab nraud hauv ob lub tsev kho mob hauv Ghana uas cuam tshuam rau ConS tsis kam.Cov zis thiab ConS tau raug coj mus kuaj (n = 246 thiab n = 96 feem) los ntawm cov neeg mob hauv ob lub tsev kho mob hauv Ghana.ConS tau txheeb xyuas siv Gram staining, coagulase test, thiab MALDI-TOF / MS, thiab cov tshuaj tiv thaiv kab mob rau 12 feem ntau siv tshuaj tua kab mob tau txiav txim siab los ntawm disk diffusion.Ntxiv mus, txoj kev tshuaj ntsuam xyuas tau tsim los rau kev txiav txim siab ntawm cuaj feem ntau siv tshuaj tua kab mob hauv Ghana los ntawm kev siv cov khoom siv ph ase extraction ua ke nrog HPLC-MS / MS siv electron spray ionization.Qhov siab tshaj plaws ntawm kev tiv thaiv rau ConS tau pom rau penicillin V (98%), trimethoprim (67%), thiab tetracycline (63%).S. haemolyticus feem ntau yog cais tawm (75%), ua raws li S. epidermidis (13%) thiab S. hominis (6%).S. haemolyticus kuj yog hom kab mob uas pom muaj kev tiv thaiv siab tshaj plaws (82%).69% ntawm cov ConS uas raug rho tawm tau ntau yam tshuaj tiv thaiv (≧ 4 tshuaj tua kab mob) thiab 45% ntawm ConS yog methicillin resistant.Cov tshuaj tua kab mob tau kuaj pom hauv 64% ntawm cov qauv kuaj zis (n = 121) qhov twg cov tshuaj tua kab mob nquag tshaj plaws yog ciprofloxacin (30%), trimethoprim (27%), thiab metronidazole (17%).Qhov kev tshawb pom loj ntawm txoj kev tshawb fawb no yog tias qhov ntau ntawm cov tshuaj tua kab mob hauv cov zis tau ntau dua li qhov siv tau tshaj tawm los ntawm cov neeg mob thiab qhov ntau ntawm cov tshuaj tiv thaiv S. haemolyticus tau ntau dua li lwm hom kab mob Cons resistant thaum kuaj pom cov tshuaj tua kab mob hauv cov zis.
