tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2- Tom ntej: Dimethyl-1,3-dioxane-4-acetate CAS: 289042-12-2
Catalog Number | xwm 93410 |
Khoom npe | tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2- Dimethyl-1,3-dioxane-4-acetate |
CAS | 289042-12-2 |
Molecular Formula | C29H40FN3O6S |
Molecular Luj | 577.71 ib |
Cov ntaub ntawv khaws cia | Ambient |
Khoom Specification
Qhov tshwm sim | Dawb hmoov |
Assay | 99% min |
Cov tshuaj tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2, 2-dimethyl-1,3-dioxane-4-acetate yog ib tug complex organic compound uas muaj peev xwm siv tau nyob rau hauv ntau yam xws li tshuaj, agrochemicals, thiab cov ntaub ntawv chemistry.Cov tshuaj no muaj ib tug tshwj xeeb tshuaj qauv uas combines txawv functional pawg, xws li ib tug ester, pyrimidine, thiab ib lub nplhaib dioxane.Lub xub ntiag ntawm cov pab pawg tert-butyl thiab acetate qhia tias muaj peev xwm ruaj khov thiab yooj yim ntawm kev tuav.Nyob rau hauv chaw ua tshuaj, qhov sib xyaw no yuav muaj peev xwm ua cov khoom siv tshuaj nquag (API) rau kev txhim kho cov tshuaj tshiab.Lub xub ntiag ntawm pawg pyrimidine qhia tias muaj peev xwm cuam tshuam nrog cov hom phiaj lom neeg, ua rau nws muaj txiaj ntsig zoo rau kev tshawb nrhiav tshuaj.Cov 4-fluorophenyl pawg txuas nrog pyrimidine paub txog nws qhov tseem ceeb hauv kev tsim tshuaj vim nws txoj kev koom tes rau kev sib koom ua ke thiab bioactivity.Nws tuaj yeem txhim kho qhov sib xyaw ua haujlwm lom neeg lossis lub hom phiaj xaiv.Cov pab pawg ethenyl tam sim no nyob rau hauv qhov sib xyaw ua ke qhia txog kev sib txawv ntawm cov qauv, uas tuaj yeem ua tau zoo rau kev hloov kho lub zog, kev ua tau zoo, thiab cov tshuaj pharmacokinetic.Cov khoom siv hloov pauv ntawm pawg ethenyl, xws li methyl thiab methylsulfonyl amino pawg, ntxiv dag zog rau cov tshuaj lom neeg sib txawv thiab tuaj yeem ua rau nws cov bioactivity lossis tshuaj zoo li cov khoom siv.Ntxiv mus, 1,3-dioxane nplhaib moiety tau cuam tshuam rau ntau yam kev siv. , nrog rau kev ua kom lub cev solubility los yog kev xa khoom rau lwm cov khoom sib txuas.Nws muaj nyob rau hauv cov compound no qhia tau hais tias nws yuav txhim kho lub compound solubility los yog stability.Apart from pharmaceutical applications, no compound kuj yuav nrhiav tau cov ntaub ntawv nyob rau hauv agrochemicals raws li ib tug tiv thaiv qoob loo.Nws tuaj yeem muaj peev xwm nthuav tawm cov tshuaj tua kab tiv thaiv kab tsuag lossis muaj lwm yam txiaj ntsig zoo rau cov nroj tsuag kev loj hlob thiab kev noj qab haus huv. Tsis tas li ntawd, cov khoom sib xyaw ua ke, xws li pawg tert-butyl thiab dioxane nplhaib, ua rau nws txaus nyiam rau kev siv hauv cov ntaub ntawv chemistry.Nws tuaj yeem ua lub tsev thaiv lossis ua ntej rau kev sib txuas ntawm cov khoom siv tshiab nrog cov khoom tshwj xeeb, xws li cov khoom siv polymeric lossis cov tshuaj tshwj xeeb. -6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate yog ib qho chaw uas muaj peev xwm siv tau hauv cov tshuaj, agrochemicals, thiab cov ntaub ntawv chemistry.Nws cov qauv tshuaj tshwj xeeb thiab cov pab pawg ua haujlwm qhia tias tsim nyog rau kev tsim tshuaj, kev tiv thaiv qoob loo, lossis kev sib txuas ntawm cov khoom tshiab.Txawm li cas los xij, kev tshawb fawb ntxiv yog xav tau los tshawb xyuas nws cov bioactivity, lub hom phiaj xaiv, cov khoom siv tshuaj, thiab kev nyab xeeb ua ntej nws tuaj yeem siv rau hauv cov ntawv thov tshwj xeeb.