Terbinafine hydrochloride CAS 78628-80-5
Catalog Number | xwm 92374 |
Khoom npe | Terbinafine hydrochloride |
CAS | 78628-80-5 |
Molecular Formula | C21H25N · HCl |
Molecular Luj | 327.89 ib |
Cov ntaub ntawv khaws cia | -15 rau -20 ° C |
Harmonized tariff Code | 29214900 ib |
Khoom Specification
Qhov tshwm sim | Dawb hmoov |
Assay | 99% min |
Melting point | 204-208 ° C |
cia temp. | 15-25 ° C |
solubility | methanol: soluble 50mg / ml |
erbinafine hydrochloride yog ib hom dav-spectrum dermatologist allyl amine antifungal tshuaj.Nws yog tsim los ntawm Swiss Novartis nyob rau hauv 1980s, thiab tshwm sim nyob rau hauv lub lag luam ntawm UK thawj zaug nyob rau hauv 1991. Pom zoo los ntawm FDA ntawm lub tebchaws United States rau OTC tshuaj nyob rau hauv 1996, thiab tshwm sim nyob rau hauv lub lag luam ntawm lub tebchaws United States nyob rau hauv tib yam. xyoo.Tam sim no, cov tshuaj tau muag hauv ntau dua 90 lub teb chaws ntawm lo lus.Nws tuaj yeem ua teeb meem tshwj xeeb rau lub caij nyoog lom neeg decomposition ntawm fungus sterol, xaiv inhibit qhov kev ua ntawm fungal squalene nplhaib oxidase, thiab inhibit squalene epoxidation nyob rau hauv tsim ntawm ungal cell membrane, yog li tua los yog inhibit lub active ingredient ntawm fungus.Haum rau kev kho mob ntawm daim tawv nqaij candidiasis, xws li tinea manuum, tinea, tinea, ringworm ntawm lub cev, tinea versicolor, nws kuj yog cov tshuaj zoo tshaj plaws rau kev kho mob ntawm onychomycosis.
Terbinafine hydrochloride nkag mus rau thawj pawg ntawm lub teb chaws tshaj tawm OTC directory nyob rau hauv 2000. Cov khoom no belongs rau cov tshuaj antifungal.Nws muaj zog cuam tshuam rau cov kab mob fungal, thiab tuaj yeem kho feem ntau ntawm cov kab mob fungal ntawm daim tawv nqaij los ntawm kev siv sab nraud.