SYBR GREEN I Nucleic Acid Gel Stain Cas: 163795-75-3 99% Khoom
Catalog Number | xwm 90236 |
Khoom npe | SYBR GREEN Kuv Nucleic Acid Gel Stain |
CAS | 163795-75-3 |
Molecular Formula | C32H37N4S |
Molecular Luj | 509.728 ib |
Cov ntaub ntawv khaws cia | -20 ° C |
Khoom Specification
Qhov tshwm sim | Dawb hmoov |
Assay | 99% |
Flow cytometry yog ib txoj hauv kev rau kev ua hauv vitro antimalarial rhiab heev rhiab heev nrog kev ua kom muaj peev xwm rau daim ntawv thov hauv thaj chaw.Peb tau tshuaj xyuas hauv vitro susceptibility rau xya tshuaj tiv thaiv kab mob malarial rau 40 tshiab P. falciparum teb cais tawm ntawm txoj kev ntws cytometry (FCM), colorimetric LDH-raws li ELISA : DELI), thiab tus qauv microscopic slide tsom xam ntawm kev loj hlob.Rau FCM, 184/280 (66%) kev soj ntsuam tau ua raws li cov qauv kev lees paub, piv rau 166/280 (59%) rau DELI.Muaj kev pom zoo zoo ntawm FCM thiab microscopy, thaum DELI nyiam tsim ntau dua ib nrab-qhov siab tshaj plaws inhibition tas li (IC50s) dua li FCM, nrog rau tag nrho kev tsis ncaj ncees ntawm 2.2-fold (Bland-Altman piv).Cov txiaj ntsig rau artesunate thiab dihydroartemisinin feem ntau cuam tshuam.Paradoxical nce nyob rau hauv cov teeb liab ntawm qhov siab heev ntawm mefloquine thiab lwm yam sib txuas tau cim ntau dua nrog qhov kev ntsuam xyuas DELI, tawm tswv yim tias cov teeb meem tawm ntawm LDH ntau lawm yuav yog lub luag haujlwm.Kev poob ntawm FCM teeb liab vim muaj kev cuam tshuam rov qab los yog kev loj hlob qeeb tau pom nyob rau hauv cov qauv me me.Cov txiaj ntsig no txuas ntxiv ua haujlwm dhau los ntawm kev siv cov cytometry ntws los txiav txim siab txog kev tiv thaiv kab mob malarial nyob rau hauv cov nqe lus ntawm cov qauv, ntau yam tshuaj, thiab kev sib piv nrog rau lwm txoj hauv kev.