N- Acetyl -L-cysteine CAS: 616-91-1 98% Dawb crystalline hmoov
| Catalog Number | xwm 90127 |
| Khoom npe | N-Acetyl-L-cysteine |
| CAS | 616-91-1 |
| Molecular Formula | C5H9NO3S |
| Molecular Luj | 163.1949 Nws |
| Cov ntaub ntawv khaws cia | 2 txog 8 ° C |
| Harmonized tariff Code | 29309016 ib |
Khoom Specification
| Melting Point | 106-112 ° C |
| Kev sib hloov tshwj xeeb | + 21 ° - + 25 ° C |
| Cov hlau hnyav | <10ppm |
| Arsenic | <1 ppm |
| pH | 2.0-2.8 Nws |
| Poob rau ziab | max 1.0% |
| Sulfate | <0.03% |
| Assay | 98% min |
| Hlau | <20 ppm |
| Residue ntawm Ignition | max .5% |
| Ammonium | <0.02% |
| cl | <0.04% |
| Qhov tshwm sim | Dawb crystalline hmoov |
| Lub Xeev Txoj Cai | > 98% |
N-Acetyl-L-cysteine yog ib qho acetylated amino acid nrog antioxidant thiab mucolytic zog.Ob qho kev ua ub no tau qhia N-Acetyl-L-cysteine tshwj xeeb hauv kev kho tshuaj kho mob cystic fibrosis, qhov twg cov tshuaj tiv thaiv antioxidant / txo tus cwj pwm ntawm cov khoom sib xyaw ua kom cov yam ntxwv ntawm lub cev redox tsis txaus ntawm CF thiab cov khoom mucolytic ntawm cov compound impede thaum lub sij hawm. congestion thiab o correlated rau lub xeev redox.Raws li ib tug mucolytic, N-Acetyl-L-cysteine ua hauj lwm rau dissipate disulfide bonds nyob rau hauv mucoproteins, loosening thiab clearing cov viscosity ntawm cov hnoos qeev.N-Acetyl-L-cysteine qhia tau hais tias pub dawb rau glutathione, ob qho tib si ua kom pom kev ua haujlwm antioxidant los ntawm lawv txoj haujlwm thiol, thiab ob qho tib si tau pom los tiv thaiv kev ntxhov siab peroxidative cuam tshuam nrog kev poob siab septic.N-Acetyl-L-cysteine kuj tau pom tias yuav ua rau apoptosis hauv vascular du leeg hlwb, qhia tias cov hlwb no teb txawv rau cov kev hloov hauv kev txo qis-oxidation xeev dua li lwm cov ntaub so ntswg uas ib txwm tiv thaiv los ntawm muaj cov tshuaj antioxidants.Qhov kev sib raug zoo tsis txaus ntseeg hauv vascular du leeg hlwb qhia N-Acetyl-L-cysteine raws li kev cog lus cuam tshuam rau arteriosclerotic proliferation ntawm cov hlwb.
Cov khoom siv tshuaj: N-acetyl-L-cysteine white crystalline hmoov, nrog qej zoo li tsw thiab qaub saj.Hygroscopic, soluble hauv dej los yog ethanol, insoluble hauv ether thiab chloroform.Nws yog acidic nyob rau hauv aqueous tov (pH2-2.75 nyob rau hauv 10g / LH2O), mp101-107 ℃ Chemicalbook.Cov khoom no yog N-acetylated derivative ntawm cysteine .Cov molecule muaj ib pab pawg sulfhydryl, uas tuaj yeem rhuav tshem cov disulfide daim ntawv cog lus (-SS-) ntawm mucin peptide daim ntawv cog lus, yog li tig lub mucin saw mus rau hauv ib qho me me molecular peptide saw, txo cov viscosity ntawm mucin, cov khoom no yog ib tug dissolving. tshuaj rau viscous sputum, purulent hnoos qeev thiab ua pa hnoos qeev.
Kev sib cuam tshuam ntawm tshuaj:
1. Tsis txhob siv ua ke nrog penicillin, cephalosporin thiab tetracycline tshuaj tua kab mob, vim tias tom kawg yuav ua tsis tau zoo.
2. Kev sib xyaw ua ke lossis kev siv lwm yam nrog isoproterenol tuaj yeem txhim kho cov nyhuv curative thiab txo qhov tsis zoo.
3. Tsis txhob kov cov khoom siv hlau thiab roj hmab, oxidants, thiab oxygen.
Siv: cov khoom siv roj ntsha, cov khoom siv raw, thiol (-SH) hauv cov molecule tuaj yeem rhuav tshem cov saw hlau disulfide (-SS) txuas cov mucin peptide saw hauv mucous phlegm.Mucin hloov tshuaj rau hauv me me molecular peptide saw, uas txo cov viscosity ntawm hnoos qeev;Nws tseem tuaj yeem rhuav tshem DNA fibers hauv cov hnoos qeev, yog li nws tuaj yeem tsis tsuas yog yaj cov hnoos qeev dawb xwb tab sis kuj muaj cov hnoos qeev purulent.
Siv: Hauv tshuaj, nws yog siv los ua phlegm-dissolving tshuaj.Rau kev tshawb fawb biochemical, nws yog siv los ua tshuaj tua kab mob rau phlegm dissolving thiab acetaminophen lom hauv tshuaj.
Siv: Rau kev tshawb fawb biochemical, hauv tshuaj, nws yog siv los ua phlegm dissolving tshuaj thiab tshuaj tua kab mob rau acetaminophen lom.
Siv: Biochemical reagents, tshuaj, cov khoom no yog siv los ua ib qho expectorant, uas tau hais tias yuav yooj yim ntxuav phlegm thiab yooj yim hnoos.Nws muaj cov nyhuv decomposition ntawm viscous sputum.Cov txheej txheem ntawm kev txiav txim yog tias pawg sulfhydryl muaj nyob rau hauv cov qauv molecular ntawm cov khoom no tuaj yeem rhuav tshem cov disulfide daim ntawv cog lus tshuaj hauv mucin polypeptide saw hauv cov hnoos qeev, decompose cov mucin, txo cov viscosity ntawm cov hnoos qeev, thiab ua kom nws liquefied thiab yooj yim rau hnoos.Nws yog qhov tsim nyog rau cov kab mob ua pa nyuaj thiab mob ntev nrog cov hnoos qeev tuab thiab nyuaj rau expectorate, nrog rau cov tsos mob tseem ceeb ntawm kev nqus dej vim kev cuam tshuam ntawm ntau cov nplaum phlegm.
Kev Siv: N-acetyl-L-cysteine tuaj yeem siv los ua cov tshuaj phlegm-dissolving.Nws yog qhov tsim nyog rau kev ua pa ua pa los ntawm qhov ntau ntawm cov nplaum phlegm obstruction.Tsis tas li ntawd, nws tseem tuaj yeem siv rau kev tshem tawm cov tshuaj acetaminophen lom.Vim tias cov khoom no muaj cov ntxhiab tsw tshwj xeeb, noj nws tuaj yeem ua rau xeev siab thiab ntuav.Nws muaj cov nyhuv stimulating ntawm txoj hlab ntsws thiab tuaj yeem ua rau bronchospasm.Nws yog siv ua ke nrog cov tshuaj bronchodilators xws li isoproterenol thiab cov tshuaj tua cov hnoos qeev kom tshem tawm cov hnoos qeev.Nws yuav tsum tsis txhob sib cuag nrog cov hlau (xws li Fe, Cu), roj hmab, oxidants, thiab lwm yam. Nws yuav tsum tsis txhob siv ua ke nrog cov tshuaj tua kab mob xws li penicillin, cephalosporin, tetracycline, thiab lwm yam, kom tsis txhob txo nws cov nyhuv antibacterial.Siv ceev faj rau cov neeg mob uas muaj mob hawb pob bronchial.
