Tom ntej: Methyl 1,2,3,4-tetra-O-acetyl-BD-glucuronate CAS: 7355-18-2 98%
Catalog Number | XD90029 |
Khoom npe | Tom ntej: Methyl 1,2,3,4-tetra-O-acetyl-BD-glucuronate |
CAS | 7355-18-2 ib |
Molecular Formula | C15H20O11 |
Molecular Luj | 376.31 ib |
Cov ntaub ntawv khaws cia | 2-8 ° C |
Harmonized tariff Code | 29389 0 |
Khoom Specification
Qhov tshwm sim | Dawb rau Yuav luag dawb hmoov rau siv lead ua |
Assay | 98% |
Methyl 1,2,3,4-tetra-O-acetyl-β-D-glucuronate tau siv rau hauv kev tshawb fawb los ntsuas kev tsim thiab kev sib txuas ntawm cov dej-soluble glucuronide derivatives ntawm camptothecin rau mob qog noj ntshav prodrμg monotherapy thiab antibody-directed enzyme prodrμg kev kho mob.Nws kuj tau siv rau hauv kev tshawb fawb los tshawb xyuas cov synthesis thiab lub luag haujlwm ntawm glycosylthio heterocycles hauv carbohydrate chemistry.
Synthesis ntawm derivatives ntawm pentopyranic acid
N4-Benzoylcytosine 1-(methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate) tau txais nrog cov txiaj ntsig ntawm 70% los ntawm glycosylation ntawm trimethylsilyl derivative ntawm N4-benzoylcytosine nrog methyl 1,2 , 3,4-tetra-O-acetyl-β-D-glucopyranuronate nyob rau hauv lub xub ntiag ntawm peb qhov sib npaug ntawm SnCl4 ua tus neeg sawv cev condensing.Cytosine 1-(β-D-glucopyranosiduronamide) (IV) - cov amide ntawm pentopyranic acid - tau raug synthesized nyob rau hauv quantitative yield los ntawm ammonolysis ntawm nucleoside (I).