L-Cystine CAS: 56-89-3 99% Dawb muaju los yog crystalline hmoov
| Catalog Number | xwm 90322 |
| Khoom npe | L-Cystine |
| CAS | 56-89-3 : kuv |
| Molecular Formula | C6H12N2O4S2 |
| Molecular Luj | 240.30 Nws |
| Cov ntaub ntawv khaws cia | Ambient |
| Harmonized tariff Code | 29309013 ib |
Khoom Specification
| Qhov tshwm sim | Dawb crystalline hmoov los yog crystalline hmoov |
| Assay | 99% |
| Qib | USP32 |
| Kev sib hloov tshwj xeeb | -215 ° rau -225 ° |
| Cov hlau hnyav | <0.0015% |
| AS | 1.5ppm max |
| SO4 | 0.040% max |
| Fe | <0.003% |
| Poob rau ziab | 0.20% max |
| Residual ntawm Ignition | 0.10% max |
| Cl | 0.10% max |
Cov qauv siv lead ua ntawm carboxypeptidase T (CpT) complexes nrog phenylalanine thiab arginine substrate analogs - benzylsuccinic acid thiab (2-guanidinoethylmercapto) succinic acid - tau txiav txim siab los ntawm txoj kev hloov molecular ntawm cov kev daws teeb meem ntawm 1.57 Å thiab 1.62 Åb rau clarroad profile. ntawm enzyme.Cov kev saib xyuas Leu211 thiab Leu254 residues (tseem muaj nyob rau hauv ob qho tib si carboxypeptidase A thiab carboxypeptidase B) tau pom tias yog cov qauv txiav txim rau kev lees paub ntawm hydrophobic substrates, whereas Asp263 yog rau kev lees paub ntawm qhov zoo them substrates.Kev hloov pauv ntawm cov kev txiav txim siab no hloov pauv cov substrate profile: CpT variant Leu211Gln tau txais carboxypeptidase B-zoo li cov khoom, thiab CpT variant Asp263Asn cov carboxypeptidase A-zoo li xaiv.Lub voj Pro248-Asp258 cuam tshuam nrog Leu254 thiab Tyr255 tau pom tias yog lub luag haujlwm rau kev lees paub ntawm substrate's C-terminal residue.Substrate binding ntawm S1 'subsite ua rau ligand-dep endent hloov ntawm lub voj no, thiab Leu254 sab saw txav induces conformation rearrangement ntawm Glu277 residue tseem ceeb heev rau catalysis.Qhov no yog qhov kev pom tshiab rau hauv substrate xaiv ntawm metallocarboxypeptidases uas qhia tau hais tias qhov tseem ceeb ntawm kev sib cuam tshuam ntawm S1 'subsite thiab catalytic center.
