Kanamycin A Sulfate CAS: 25389-94-0 Dawb crystalline hmoov
Catalog Number | xwm 90363 |
Khoom npe | Kanamycin Ib Sulfate |
CAS | 25389-94-0 |
Molecular Formula | C18H36N4O11 · H2O4S |
Molecular Luj | 582.58 ib |
Cov ntaub ntawv khaws cia | 15 txog 30 ° C |
Harmonized tariff Code | 29419000 ib |
Khoom Specification
Qib | USP |
pH | 6.5-8.5 Nws |
Cov kab mob endotoxin | <0.60EU/mg |
Poob rau ziab | 4.0% max |
Solubility | Dawb soluble hauv dej, insoluble hauv acetone hauv ethyl acetate thiab hauv benzene |
Assay | > 750 ug/mg |
Sulfated tshauv | 11 - 17.7% |
Residue ntawm Ignition | <1.0% |
Kev sib hloov kho qhov muag tshwj xeeb | +112-123 |
Residual Solvents | Ethanol 2000ppm Max |
Tag nrho cov impurities | 3.0% max |
Qhov tshwm sim | Dawb crystalline hmoov |
Hnub tsim khoom | TBC |
Kanamycin B | 1.5% max |
Tej yam tsis paub impurity | 0.45% max |
Microbial txwv | 25 cfu/g Max |
Antimicrobial proteins / peptides tau nyiam ntau yam vim tias lawv muaj peev xwm siv tau hauv kev lag luam.Nyob rau hauv txoj kev tshawb no, ib qho thermostable antimicrobial protein (BSAMP) tau ntxuav los ntawm kab lis kev cai supernatant ntawm Bacillus subtilis FB123 los ntawm ammonium sulfate nag lossis daus, gel chromatography ntawm Sephacryl S-200 High Resolution, thiab ion exchange chromatography ntawm DEAE Sepharose Fast Flow kem.Qhov hnyav molecular ntawm BSAMP purified yog 54 kDa, raws li kev kwv yees los ntawm sodium dodecyl sulfate-polyacrylamide gel electrophoresis ob qho tib si nyob rau hauv tsis muaj thiab muaj β-mercaptoethanol.Nws qhov taw tes isoelectric tau txiav txim siab yog 5.24 los ntawm isoelectric focusing electrophoresis.Periodic acid-Schiff staining qhia BSAMP los ua glycoprotein.Kev ua haujlwm siab tshaj plaws tau txais ntawm pH 6.0, nrog ntau dua 79% kev ua haujlwm siab tshaj plaws khaws cia ntawm pH 3.0-5.0 thiab pH 7.0-9.0, feem.BSAMP tau pom tias muaj qhov kub thiab txias heev, vim tias nws cov haujlwm tsis hloov pauv pom tseeb tom qab kev kho mob ntawm 100 ° C.Txawm li cas los xij, nws yog ib feem rhiab rau papain, trypsin, thiab alkali proteases.Thaum kawg, cov kab mob protein tau nthuav tawm dav-spectrum antimicrobial kev ua haujlwm tawm tsam ntau yam kab mob pathogenic.Cov kev tshawb pom no tau qhia tias BSAMP yuav tsum tau tsim ntxiv los ua cov tshuaj tua kab mob ntuj tsim los tiv thaiv kab mob hauv aquiculture thiab kev ua liaj ua teb.