Hygromycin B CAS: 31282-04-9 Buff hmoov
| Catalog Number | xwm 90374 |
| Khoom npe | Hygromycin B |
| CAS | 31282-04-9 |
| Molecular Formula | C20H37N3O13 |
| Molecular Luj | 527.52 ib |
| Cov ntaub ntawv khaws cia | 2 txog 8 ° C |
| Harmonized tariff Code | 2941900000 ib |
Khoom Specification
| Cov hlau hnyav | 20 mg/kg max |
| pH | 7-9.5 Nws |
| Assay | 99% |
| Poob rau ziab | 5% max |
| kev ua si | 950u/mg min |
| Ammonium | 1% max |
| Sulfated tshauv | 5% max |
| Qhov tshwm sim | Buff hmoov |
| Purity TLC | > 90% |
Chronological aging ntawm poov xab hlwb feem ntau yog siv los ua tus qauv rau kev laus ntawm tib neeg post-mitotic hlwb.Cov poov xab Saccharomyces cerevisiae zus ntawm cov piam thaj nyob rau hauv lub xub ntiag ntawm ammonium sulphate yog tsuas yog siv nyob rau hauv cov poov xab aging kev tshawb fawb.Peb tau soj ntsuam kev laus ntawm cov poov xab Hansenula polymorpha loj hlob ntawm cov xwm txheej uas yuav tsum muaj cov txheej txheem peroxisome metabolism hauv kev loj hlob.Lub neej ntev ntawm H. polymorpha yog qhov zoo dua qub thaum cov hlwb loj hlob ntawm methanol lossis ethanol, metabolized los ntawm peroxisome enzymes, txheeb ze rau kev loj hlob ntawm cov piam thaj. uas tsis xav tau peroxisomes.Lub neej luv luv ntawm H. polymorpha ntawm qabzib feem ntau yog vim qhov nruab nrab acidification, qhov feem ntau ROS tsis ua lub luag haujlwm tseem ceeb.Kev loj hlob ntawm cov hlwb ntawm methanol / methylamine es tsis txhob methanol / ammonium sulphate ua rau muaj kev ua neej ntxiv.Qhov no tsis cuam tshuam rau nruab nrab acidification.Peb qhia tau hais tias oxidation ntawm methylamine los ntawm peroxisomal amine oxidase ntawm carbon starvation tej yam kev mob yog lub luag hauj lwm rau lifespan extension.Cov khoom methylamine oxidation formaldehyde yog ntxiv oxidized uas ua rau NADH tiam, uas ua rau muaj zog ATP tiam thiab txo ROS theem nyob rau hauv cov theem nyob ruaj ruaj.Peb txiav txim siab tias thawj peroxisome metabolism txhim kho chronological lifespan ntawm H. polymorpha.Ntxiv mus, muaj peev xwm tsim NADH ntawm carbon starvation tej yam kev mob los ntawm ib tug organic nitrogen qhov chaw txhawb ntxiv extension ntawm lub neej ntawm lub cell.Yog li ntawd, kev txhais lus ntawm CLS kev txheeb xyuas hauv cov poov xab yuav tsum muaj qhov cuam tshuam rau lub zog ntawm lub cell.
