Erythromycin CAS: 114-07-8 99% Dawb crystalline hmoov
Catalog Number | xwm 90353 |
Khoom npe | Erythromycin |
CAS | 114-07-8 ib |
Molecular Formula | C37H67NO13 |
Molecular Luj | 733.93 ib |
Cov ntaub ntawv khaws cia | Ambient |
Harmonized tariff Code | 29415 000 Nws |
Khoom Specification
Kev txheeb xyuas | IR absorption spectrum sib piv nrog USP RS |
Dej | 10% max |
Ethanol | 0.5% max |
Residue ntawm Ignition | 0.2% max |
Assay | 99% |
Kev sib hloov tshwj xeeb | -71 ° rau -78 ° |
Qhov tshwm sim | Dawb crystalline hmoov |
Crystallinity | Ua tau raws li qhov yuav tsum tau ua |
Erythromycin B | 12.0% max |
ErythromycinC | 5.0% max |
Kev txwv ntawm thiocyanate | 0.3% max |
Propanol | 0.5% max |
N-butyl acetate hmoov | 0.5% max |
Erythromycin A enol ether | 0.3% max |
Txhua yam khoom muaj feem xyuam rau tus kheej | 3.0% max |
Hauv txoj kev tshawb fawb tam sim no, peb tau tshuaj xyuas kev sib cuam tshuam ntawm cov tshuaj tiv thaiv kab mob nrog plaub tus qauv lipid daim nyias nyias uas ua rau cov kab mob ntawm tes thiab Gram-positive thiab-negative bacterial membranes thiab soj ntsuam cov kev sib txuas kinetics siv peb cov txheej txheem plasmon resonance (SPR).Kev xaiv thiab tshwj xeeb khi cov yam ntxwv ntawm cov tshuaj tiv thaiv kab mob rau cov lipid daim nyias nyias tau kwv yees, thiab cov kinetic tsis tau txheeb xyuas los ntawm kev siv ob lub xeev cov tshuaj tiv thaiv qauv.Reproducible tsom xam ntawm binding kinetics tau pom.Vancomyicn, teicoplanin, erythromycin, thiab linezolid pom me ntsis kev cuam tshuam nrog plaub lipid membranes hauv SPR system.Ntawm qhov tod tes, vancomycin analogues pom kev cuam tshuam nrog cov qauv lipid membranes hauv SPR system.Kev xaiv thiab kev khi tshwj xeeb ntawm vancomycin analogues rau cov lipid daim nyias nyias yog sib tham los ntawm cov ntaub ntawv rau hauv vitro antibacterial kev ua ub no thiab peb cov ntaub ntawv ntawm kev sib koom ua ke ntawm D-alanyl-D-ala cuaj terminus ntawm pentapeptide cell phab ntsa tau los ntawm SPR.Cov txheej txheem ntawm kev tiv thaiv kab mob tiv thaiv Staphylococcus aureus thiab vancomycin-resistant enterococci tuaj yeem raug soj ntsuam los ntawm kev siv cov kev sib txuas uas tau txais nrog peb cov txheej txheem SPR.Cov txiaj ntsig tau qhia tias txoj kev SPR tuaj yeem siv dav los kwv yees cov yam ntxwv ntawm kev sib khi, xws li kev xaiv thiab kev tshwj xeeb, ntawm ntau cov tshuaj tiv thaiv kab mob rau lipid membranes.