D-Leucine Cas: 328-38-1 99% Dawb hmoov
| Catalog Number | xwm 90305 |
| Khoom npe | D-Leucine |
| CAS | 328-38-1 : kuv |
| Molecular Formula | C6H13NO2 |
| Molecular Luj | 131.17292 ib |
| Cov ntaub ntawv khaws cia | Ambient |
| Harmonized tariff Code | 29224985 ib |
Khoom Specification
| Kev sib hloov tshwj xeeb | -14-16 |
| AS | <1 ppm |
| Pb | <10ppm |
| Poob rau ziab | <0.20% |
| Assay | 99% |
| Residue ntawm Ignition | <0.10% |
| Cl | <0.020% |
| Qhov tshwm sim | Dawb hmoov |
Ib puag ncig yam tseem ceeb, xws li macronutrient muaj pes tsawg leeg ntawm cov khoom noj, tuaj yeem muaj kev cuam tshuam loj heev rau kev pheej hmoo ntawm ntshav qab zib thiab metabolic syndrome.Hauv kev tshawb fawb tam sim no peb pom tau hais tias yuav ua li cas ib qho kev noj haus yooj yim - leucine - tuaj yeem hloov kho cov tshuaj insulin los ntawm kev ua haujlwm ntawm ntau cov ntaub so ntswg thiab ntau theem ntawm cov metabolism.Cov nas tau muab tso rau hauv ib qho kev noj zaub mov zoo lossis muaj roj ntau (HFD).Dietary leucine tau muab faib ua ob npaug los ntawm kev ntxiv rau cov dej haus.mRNA, protein thiab ua tiav cov txheej txheem metabolomic tau soj ntsuam hauv cov ntaub so ntswg loj ntawm cov tshuaj insulin thiab cov ntshav, thiab cuam tshuam nrog kev hloov pauv hauv cov piam thaj hauv tsev thiab cov cim qhia ntawm insulin.Tom qab 8 lub lis piam ntawm HFD, nas tau tsim rog rog, rog rog, inflammatory kev hloov pauv hauv cov ntaub so ntswg adipose thiab insulin tsis kam ntawm qib IRS-1 phosphorylation, nrog rau kev hloov pauv hauv metabolomic profile ntawm amino acid metabolites, TCA cycle intermediates, qabzib thiab cov roj cholesterol metabolites. , thiab fatty acids nyob rau hauv daim siab, nqaij, rog thiab ntshav.Kev noj zaub mov ob npaug ntawm leucine reve rsed ntau ntawm cov metabolite abnormality thiab ua rau muaj kev txhim kho hauv cov piam thaj thiab insulin signaling yam tsis muaj kev hloov pauv zaub mov lossis qhov hnyav nce.Kev noj zaub mov ntau ntxiv kuj tseem cuam tshuam nrog kev txo qis hauv hepatic steatosis thiab txo qhov mob ntawm cov ntaub so ntswg adipose.Cov kev hloov pauv no tau tshwm sim txawm tias muaj kev nce hauv insulin-stimulated phosphorylation ntawm p70S6 kinase qhia txog kev ua kom zoo dua ntawm mTOR, ib qho tshwm sim feem ntau cuam tshuam nrog insulin tsis kam.Cov ntaub ntawv no qhia tias kev hloov pauv me me hauv ib puag ncig ib puag ncig / cov khoom noj tuaj yeem hloov kho ntau yam metabolic thiab qhia txoj hauv kev thiab hloov kho HFD induced metabolic syndrome los ntawm kev ua haujlwm ntawm cov txheej txheem ntawm ntau cov ntaub so ntswg.Cov ntaub ntawv no tseem qhia tau hais tias kev noj zaub mov ntau ntxiv tuaj yeem ua rau muaj kev cuam tshuam hauv kev tswj hwm kev rog rog txog cov tshuaj insulin.
