Cov khoom

Clopidogrel camphorsulfonate yog ib qho tshuaj sib xyaw nrog cov tshuaj formula C16H16ClNO2S·C10H16O4S.Nws feem ntau hu ua Clopidogrel S-oxide camphorsulfonate los yog Clopidogrel CAMS.Cov tshuaj no yog ib tug chiral derivative ntawm clopidogrel, uas yog ib tug dav siv tshuaj antiplatelet.Cov thawj siv ntawm Clopidogrel camphorsulfonate yog ib tug active ingredient nyob rau hauv lub formulation ntawm antiplatelet tshuaj.Nws ua haujlwm los ntawm inhibiting platelet aggregation, tiv thaiv cov ntshav txhaws, thiab txo cov kev pheej hmoo ntawm cov kab mob plawv.Cov compound tshwj xeeb yog tsom rau P2Y12 receptor ntawm platelets, yog li thaiv cov txheej txheem ua kom thiab inhibiting platelet aggregation.Cov txheej txheem ntawm kev ua no ua rau Clopidogrel camphorsulfonate muaj txiaj ntsig zoo hauv kev tiv thaiv cov hlab ntsha ntawm cov hlab ntsha thiab txo qhov tshwm sim ntawm cov xwm txheej tsis zoo ntawm cov hlab plawv, suav nrog kev mob plawv thiab mob stroke.Thaum noj, nws nkag mus rau hauv metabolic hloov dua siab tshiab nyob rau hauv lub siab, uas ua rau tsim cov active metabolite.Cov metabolite nquag no ces irreversibly khi rau P2Y12 receptor, exerting nws antiplatelet teebmeem rau lub sij hawm ntev.Cov tshuaj muaj lub sijhawm ntev ntawm kev ua haujlwm, yuav tsum tau noj ib zaug ib hnub nyob rau hauv feem ntau.Nyob rau hauv kev kho mob, Clopidogrel camphorsulfonate feem ntau yog muab rau cov neeg mob uas mob plawv mob, xws li tsis ruaj tsis khov angina thiab myocardial infarction, los yog cov neeg uas tau undergone percutaneous coronary. Kev cuam tshuam (PCI) nrog stent tso.Nws kuj tau siv dav los tiv thaiv qhov tshwm sim ntawm cov xwm txheej thrombotic hauv cov neeg mob uas muaj keeb kwm ntawm mob stroke lossis kab mob peripheral artery.Kev siv Clopidogrel camphorsulfonate feem ntau ua ke nrog cov tshuaj aspirin qis los ua kom zoo rau kev kho mob antiplatelet.Nws yog ib qho tseem ceeb kom nco ntsoov tias Clopidogrel camphorsulfonate yuav tsum tsuas yog siv nyob rau hauv kev saib xyuas ntawm tus kws kho mob, vim nws yuav cuam tshuam nrog lwm cov tshuaj los yog muaj contraindications hauv qee yam. cov neeg mob.Qhov ntau npaum li cas thiab lub sijhawm ntawm kev kho mob yuav txawv nyob ntawm tus neeg mob tus mob, thiab kev saib xyuas ntawm platelet kev ua haujlwm thiab kev kuaj ntshav tsis tu ncua yuav tsum tau ua kom ntseeg tau tias cov txiaj ntsig kho tau zoo. tshwj xeeb tshaj yog cov uas cuam tshuam txog arterial thrombosis.Nws cov khoom antiplatelet thiab xaiv inhibition ntawm P2Y12 receptor ua rau nws muaj txiaj ntsig zoo rau kev txo qis kev pheej hmoo ntawm kev mob plawv.Txawm li cas los xij, ib yam li txhua yam tshuaj, yuav tsum tau ceev faj txog kev siv, thiab cov neeg mob yuav tsum ua raws li lawv tus kws kho mob cov lus pom zoo thiab kev taw qhia.