1,1-Cyclobutanedicarboxylatodiammineplatinum (II) Cas: 41575-94-4
| Catalog Number | xwm 90684 |
| Khoom npe | 1,1-Cyclobutanedicarboxylatodiammineplatinum (II) |
| CAS | 41575-94-4 |
| Molecular Formula | C6H12N2O4 Pt |
| Molecular Luj | 371.25 Nws |
| Cov ntaub ntawv khaws cia | 2-8 ° C |
| Harmonized tariff Code | 28 4390 |
Khoom Specification
| Qhov tshwm sim | Dawb mus rau dawb hmoov |
| Assay | 99% |
| Dej | ≤ 0.5% |
| Poob rau ziab | ≤ 0.5% |
| Chlorides | ≤100ppm |
| Yam khoom muaj feem | ≤ 0.25% |
| Tej yam tsis meej tsis meej | ≤ 0.1% |
| Tag nrho lwm yam impurities | ≤ 0.5% |
| 1,1-Cyclobutanedicarboxylic acid | ≤ 0.5% |
Thib ob tiam platinum complex antineoplastic tshuaj.Lub antitumor spectrum thiab antitumor kev ua haujlwm zoo ib yam li cov cisplatin, tab sis cov dej solubility zoo dua li cisplatin, thiab cov tshuaj lom rau lub raum kuj qis dua.Nws muaj cov txiaj ntsig zoo rau kev mob qog noj ntshav me me, mob qog noj ntshav ntawm zes qe menyuam, lub taub hau thiab caj dab squamous cell carcinoma, qog nqaij hlav, qog nqaij hlav malignant, thiab lwm yam.
Cov tshuaj tiv thaiv kab mob platinum thib ob muaj qhov ua haujlwm zoo ib yam thiab siv li cisplatin.Nws muaj zog ntau dua li cisplatin rau qee cov qog nqaij hlav, thiab muaj zog dua cisplatin ua radiosensitizer nyob rau hauv cov mob hypoxic.Feem ntau yog siv rau cov qog nqaij hlav zes qe menyuam, qog nqaij hlav qog nqaij hlav, qog nqaij hlav qog nqaij hlav me me thiab mob qog noj ntshav hauv lub taub hau thiab caj dab.
Carboplatin yog cov tshuaj tiv thaiv kab mob platinum uas ua rau DNA puas tsuaj los ntawm kev tsim intrachain conjugation rau guanine residues uas nyob ib sab.Cov nyhuv antitumor ntawm cov tshuaj no yog ua tiav los ntawm kev poob ntawm DNA mismatch kho (MMR tshuaj tiv thaiv) kev ua thiab induction ntawm programmed cell tuag.
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