paj_banner

Cov khoom

Tom ntej: Trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylicacid CAS: 169248-97-9

Lus piav qhia luv luv:

Catalog Number: xwm 93466
Cas: 169248-97-9
Molecular Formula: C17H20F3NO4
Molecular Luj: 359.34 ib
Muaj: Hauv Tshuag
Nqe:  
Prepack:  
Ntim Pob: Thov Quote

 


Product Detail

Khoom cim npe

Catalog Number xwm 93466
Khoom npe Trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylicacid
CAS 169248-97-9
Molecular Formula C17H20F3NO4
Molecular Luj 359.34 ib
Cov ntaub ntawv khaws cia Ambient

 

Khoom Specification

Qhov tshwm sim Dawb hmoov
Assay 99% min

 

Trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl) phenyl) pyrrolidine-3-carboxylic acid yog cov tshuaj lom neeg uas muaj ntau yam kev siv hauv thaj chaw ntawm cov organic synthesis thiab kev tshawb fawb tshuaj.Nws yog tus cwj pwm los ntawm qhov muaj lub nplhaib pyrrolidine hloov nrog tert-butoxycarbonyl (Boc) tiv thaiv pab pawg ntawm nitrogen atom thiab ib pawg trifluoromethyl ntawm lub nplhaib phenyl.Ib qho tseem ceeb ntawm kev siv trans-1-(tert-Butoxycarbonyl)- 4-(3-(trifluoromethyl)phenyl) pyrrolidine-3-carboxylic acid yog ib qho nruab nrab hauv kev sib txuas ntawm lwm cov organic tebchaw.Nws cov qauv tshwj xeeb thiab cov pab pawg ua haujlwm ua rau nws muaj ntau lub tsev thaiv rau kev tsim kho ntawm cov molecules complex.Pab pawg Boc ua haujlwm pab pawg tiv thaiv, uas tuaj yeem xaiv tau tshem tawm raws li cov xwm txheej tshwj xeeb los nthuav tawm qhov chaw reactive rau kev hloov kho ntxiv.Qhov no tso cai rau kev tswj hwm thiab meej cov organic transformations.The trifluoromethyl pawg hauv trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid kuj imparts tseem ceeb zog thiab muaj peev xwm siv tau.Trifluoromethyl pawg paub txog lawv qhov kev rho tawm hluav taws xob thiab lipophilicity, uas tuaj yeem txhim kho lub zog, metabolic stability, thiab bioavailability ntawm cov neeg siv tshuaj.Tsis tas li ntawd, pawg trifluoromethyl tuaj yeem hloov kho lub zog ntawm lub cev ntawm cov khoom sib txuas, cuam tshuam rau solubility, lipophilicity, thiab receptor binding affinity. Tsis tas li ntawd, trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3- carboxylic acid tuaj yeem nthuav tawm kev ua haujlwm lom neeg nws tus kheej lossis ua ib qho tshuaj.Prodrugs yog cov tshuaj lom neeg tsis muaj zog uas ua rau muaj tshuaj lom neeg lossis cov tshuaj enzymatic hloov pauv hauv lub cev kom hloov mus rau cov tshuaj nquag.Qee qhov xwm txheej, pawg tiv thaiv Boc tuaj yeem raug xaiv tshem tawm hauv vivo, ua kom cov khoom sib xyaw ua kom muaj txiaj ntsig zoo rau kev kho mob.Thaum cov ntawv thov tshwj xeeb thiab muaj peev xwm siv rau trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)) phenyl) pyrrolidine-3-carboxylic acid muaj ntau, kev tshawb nrhiav ntxiv thiab kev tshawb fawb yog tsim nyog los tshawb txog nws lub peev xwm.Qhov no feem ntau suav nrog kev kho tshuaj chemistry optimization, kev tshawb fawb txog kev sib raug zoo-kev sib raug zoo, thiab kev ntsuam xyuas lom neeg.Los ntawm kev nkag siab zoo txog cov khoom sib xyaw thiab kev ua kom muaj zog, cov kws tshawb fawb tuaj yeem ntsuas nws qhov tsim nyog rau kev tsom mus rau cov kab mob tshwj xeeb lossis cov xwm txheej, ua rau kev txhim kho cov tshuaj tshiab los yog cov tshuaj catalytic yav tom ntej.


  • Yav dhau los:
  • Tom ntej:

  • Kaw

    Tom ntej: Trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylicacid CAS: 169248-97-9