Streptavidin los ntawm Streptomyces avidinii CAS: 9013-20-1
Catalog Number | xwm 90329 |
Khoom npe | Streptavidin los ntawm Streptomyces avidinii |
CAS | 9013-20-1 |
Molecular Formula | C14H17BrClNO2S |
Molecular Luj | 378.71 ib |
Cov ntaub ntawv khaws cia | -15 rau -20 ° C |
Harmonized tariff Code | 3 5040090 |
Khoom Specification
Qhov tshwm sim | Dawb hmoov |
Assay | 99% |
Kev tshawb fawb siv nkaus xwb, tsis yog siv rau tib neeg | kev tshawb fawb siv xwb, tsis yog rau tib neeg siv |
Alkyne-hinged 3-fluorosialyl fluoride (DFSA) uas muaj ib pawg alkyne tau pom tias yog lub hom phiaj ntawm lub hom phiaj tshwj xeeb irreversible inhibitor ntawm sialidases.Cov ester-tiv thaiv analog DFSA (PDFSA) yog ib qho membrane-permeable precursor ntawm DFSA tsim los siv rau hauv cov hlwb nyob, thiab nws tau pom tias tsim covalent adducts nrog tus kab mob, kab mob, thiab tib neeg sialidases.fluorosialyl-enzyme adduct tuaj yeem txuas nrog azide-annexed biotin los ntawm kev nyem cov tshuaj tiv thaiv thiab kuaj pom los ntawm cov cim qhia tshwj xeeb ntawm streptavidin.Ua kua chromatography-mass spectrometry/mass spectrometry tsom xam ntawm cov tryptic peptide fragments qhia tias 3-fluorosialyl moiety hloov tyrosine residues ntawm sialidases.DFSA tau siv los ua kom pom tus kab mob khaub thuas thiab kuaj pom tus kab mob kis mus rau cov tshuaj tiv thaiv kab mob khaub thuas oseltamivir acid, thaum PDFSA tau siv rau hauv qhov xwm txheej ntawm qhov kev hloov pauv ntawm sialidase kev ua hauv cov hlwb nyob.