Penicillin G potassium ntsev CAS: 113-98-4 99% Dawb hmoov
| Catalog Number | xwm 90351 |
| Khoom npe | Penicillin G potassium ntsev |
| CAS | 113-98-4 ib |
| Molecular Formula | C16H17KN2O4S |
| Molecular Luj | 372.48 ib |
| Cov ntaub ntawv khaws cia | Ambient |
| Harmonized tariff Code | 29411000 ib |
Khoom Specification
| Poob rau ziab | <1.0% |
| Xim ntawm Kev daws | Tsis muaj xim ntau dua li siv Y2 lossis YG2 ntawm ntau qhov kev siv |
| pH | 5-7.5 |
| Yam khoom muaj feem | <1.0% |
| Assay | 99% |
| Muaj peev xwm | 1440-1680u / mg |
| Qhov tshwm sim | Dawb mus yuav luag dawb crystalline hmoov |
| Clarity of Solution | Tsis ntau tshaj opalescent tshaj qhov kev siv ncua kev kawm 1 |
| Kev xa tawm | 90% NLT |
| Butyl acetate hmoov | NMT 0.05% |
| Butanol | NMT 0.12% |
e tau piav qhia yav dhau los tias autoinducer molecule, txheeb xyuas tias yog 1,3-diaminopropane (1,3-DAP), yog zais los ntawm Penicillium chrysogenum thiab Acremonium chrysogenum.Siv pH-tswj fermentor kab lis kev cai peb tau pom hauv txoj haujlwm no tias 1,3-DAP thiab spermidine kom meej meej txhawb cov biosynthesis ntawm benzylpenicillin hauv P. chrysogenum, ob qho tib si hauv kev txhais thiab hauv cov tshuaj penicillin complex.Ob leeg 1,3-DAP thiab spermidine, tab sis tsis yog putrescine (1,4-diaminobutane), ua rau muaj kev nce siab hauv cov ntawv sau tseg ntawm penicillin biosynthetic noob pcbAB, pcbC thiab penDE.Cov polyamines no tsis cuam tshuam rau kev qhia ntawm lub ntiaj teb pH-kev nyuaj siab regulator pacC noob, yog li tsis suav nrog cov nyhuv ntawm 1,3-DAP thiab spermidine yog vim muaj kev hloov kho ntawm pH tswj mechanism.Kev nthuav qhia ntawm peb penicillin biosynthetic noob yog txo qis hauv ib qho laeA-knock-down mutant ntawm P. chrysogenum, uas ua rau qis heev ntawm benzylpenicillin.Interestingly, 1,3-DAP thiab spermidine revert t nws cov nyhuv ntawm laeA knock-down mutation, tag nrho rov qab cov qib ntawm penicillin ntau lawm.Tsis tas li ntawd, 1,3-DAP thiab spermidine txhim kho qhov kev qhia ntawm laeA hauv niam txiv txoj kev mob thiab rov qab kho cov qib ntawm laeA cov ntaub ntawv pov thawj hauv laeA knock-down mutant.Ua ke cov txiaj ntsig no qhia tau hais tias cov txiaj ntsig zoo ntawm inducer molecules 1,3-DAP thiab spermidine yog exerted, tsawg kawg hauv ib feem, los ntawm kev txhawb nqa ntawm kev qhia ntawm laeA, tus tswj hwm thoob ntiaj teb uas ua rau epigenetically ntawm kev qhia ntawm cov noob metabolite theem nrab. los ntawm heterochromatin reorganization.
