L-Alanine CAS: 56-41-7 99% Dawb crystalline hmoov
| Catalog Number | xwm 90326 |
| Khoom npe | D-Alanine |
| CAS | 338-69-2 : kuv |
| Molecular Formula | C3H7NO2 |
| Molecular Luj | 89.09 ib |
| Cov ntaub ntawv khaws cia | Ambient |
| Harmonized tariff Code | 29224985 ib |
Khoom Specification
| Qhov tshwm sim | Dawb crystalline hmoov |
| Assay | 98.5 - 101.5% |
| Kev sib hloov tshwj xeeb | +13.7 - +15.1 |
| Cov hlau hnyav | <0.0015% |
| pH | 5.5-7 |
| SO4 | <0.03% |
| Poob rau ziab | <0.2% |
| Hlau | <0.003% |
| Residue ntawm Ignition | <0.15% |
| Particle Loj | 200 ua |
| Cl | <0.05% |
| Qib ntawm cov pa phem tsis tu ncua | Tsis muaj kuab paug |
γ-Glutamyltranspeptidases (γ-GTs) tshem tawm γ-glutamyl amide daim ntawv cog lus ntawm glutathione thiab hloov cov pawg γ-glutamyl tso rau hauv dej (hydrolysis) lossis txais cov amino acids (transpeptidation).Cov enzymes ubiquitous no ua lub luag haujlwm tseem ceeb hauv biosynthesis thiab degradation ntawm glutathione, thiab hauv xenobiotic detoxification.Ntawm no peb qhia txog 3Å daws teeb meem siv lead ua qauv ntawm Bacillus licheniformis γ-GT (BlGT) thiab ntawm nws txoj kev nrog l-Glu.X-ray cov qauv paub meej tias BlGT belongs rau N-terminal nucleophilic hydrolase superfamily thiab qhia tias cov protein muaj qhov qhib qhov chaw ua haujlwm zoo ib yam li qhov uas tau tshaj tawm rau homologous enzyme los ntawm Bacillus subtilis, tab sis txawv ntawm cov kev soj ntsuam rau tib neeg γ-GT thiab rau γ-GTs los ntawm lwm yam kab mob.Cov ntaub ntawv qhia tias kev khi ntawm l-Glu induces ib reordering ntawm C-terminal tail ntawm BlGT loj subunit thiab tso cai rau kev txheeb xyuas ntawm ib pawg ntawm cov kua qaub residues uas muaj feem cuam tshuam rau kev lees paub ntawm ib tug hlau ion.Nws lub luag hauj lwm ntawm cov residues nyob rau hauv conformational stability ntawm BlGT tau kawm los ntawm characterizing lub autoprocessing, enzymatic kev ua si, tshuaj thiab thermal denaturation ntawm plaub tshiab Ala ib tug mutants.Cov txiaj ntsig tau pom tias kev hloov ntawm Asp568 nrog Ala cuam tshuam rau ob qho tib si autoprocessing thiab kev ruaj ntseg ntawm cov protein.
