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Furazolidone CAS 67-45-8

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Catalog Number: xwm 91885
Cas: 67-45-8 : kuv
Molecular Formula: C8H7N3O 5
Molecular Luj: 225.16 Nws
Muaj: Hauv Tshuag
Nqe:  
Prepack:  
Ntim Pob: Thov Quote

 


Product Detail

Khoom cim npe

Catalog Number xwm 91885
Khoom npe Furazolidone
CAS 67-45-8 : kuv
Molecular Formula C8H7N3O 5
Molecular Luj 225.16 Nws
Cov ntaub ntawv khaws cia Ambient
Harmonized tariff Code 293499 0

 

Khoom Specification

Qhov tshwm sim Cov hmoov daj
Assay 99% min
Melting point 254-256 ° C (Lub Kaum Ob Hlis)
Boiling point 366.66 ° C (kwv yees kwv yees)
ceev 1.5406 (zeeg)
Refractive Index 1.7180 (kwv yees)
Fp 2 ° C
solubility formic acid: soluble 50mg / mL
pka ua -1.98 ± 0.20 (Kev kwv yees)
rhiab heev Lub teeb Sensitive
lw max 365nm (DMSO) (lit.)
Kev ruaj ntseg ruaj khov.Hluav taws kub.Incompatible nrog muaj zog oxidizing neeg sawv cev.

 

Cov tshuaj tua kab mob ntawm furazolidone zoo ib yam li furazolidone.Raws li cov tshuaj tiv thaiv kab mob, nws muaj txiaj ntsig zoo hauv kev kho Salmonella, Shigella, Escherichia coli, Proteus, Streptococcus, thiab Staphylococcus aureus.Cov kab mob tsis yooj yim los tsim cov tshuaj tiv thaiv cov tshuaj no.Nws kuj tsis muaj qhov sib txawv nrog cov tshuaj tua kab mob sulfa.Nws yog tsuas yog siv rau kev kho mob ntawm dysentery, enteritis, typhoid, paratyphoid thiab tshuaj pleev rau qhov chaw mos trichomoniasis.
2. Cov khoom yog ib tug fungicide uas muaj ib tug dav antibacterial spectrum.Raws li cov tshuaj tiv thaiv kab mob, nws muaj txiaj ntsig zoo rau kev kho ntau yam kab mob Gram-zoo thiab tsis zoo xws li Escherichia coli, Bacillus anthracis, thiab Paratyphoid bacilli.Nws tsis yog tsuas yog siv tau rau hauv kev kho mob dysentery, enteritis, tab sis kuj siv rau kev kho mob ntawm qhov chaw mos.Hauv xyoo tas los no, nws muaj txiaj ntsig zoo rau kev kho mob typhoid fever.Raws li ib qho ntxiv rau tsiaj cov tshuaj thiab haus dej haus, nws muaj cov tshuaj tua kab mob tshwj xeeb ntawm Salmonella, Escherichia coli thiab Salmonella pullorum thiab tseem muaj qee yam cuam tshuam rau cov protozoa (cov kab mob coccidia, thiab lwm yam) thiab kom lawv tsis tshua muaj evolve tshuaj tiv thaiv.Ib qho me me ntawm furazolidone tau siv rau lwm yam kev siv (xws li dej-soluble xim thiab ntawv pulp) ua fungicides.
3. Nws yog ib qho tshuaj tiv thaiv kab mob siv los tiv thaiv kab mob ntawm txoj hnyuv.
4. Furazolidone, raws li ib tug fungicide, muaj ib tug dav antibacterial spectrum.Cov kab mob uas raug mob tshaj plaws yog Escherichia coli, Bacillus anthracis, paratyphoid qws, Shigella, thiab Klebsiella pneumoniae.Salmonella typhi kuj tseem ceeb rau nws.Nws yog tsuas yog siv los kho cov kab mob uas muaj kab mob ua rau mob plab, enteritis, thiab kab mob cholera.Nws kuj tseem siv tau rau kev kho mob typhoid, paratyphoid, giardiasis, thiab trichomoniasis.Kev sib xyaw nrog cov tshuaj tiv thaiv acid tuaj yeem siv los kho Helicobacter pylori-induced gastric o.Khoom: daj hmoov los yog crystalline hmoov, tsis muaj ntxhiab, ua ntej tasteless thiab tom qab ntawd ua iab me ntsis;me ntsis soluble hauv dej thiab ethanol;me ntsis soluble hauv chloroform thiab insoluble hauv ether, soluble hauv dimethylformamide thiab nitromethane.Mp: 255 rau 259 ° C.Decompose thaum lub dissolution.

Furazolidone yog siv rau hauv cov kab mob hauv plab hnyuv thiab vaginitis.Nws yog tsuas yog siv nyob rau hauv cov teb chaws tsim los kho cov kab mob raws plab ntawm txawv etiology, tab sis nws tsis yog cov tshuaj ntawm kev xaiv yog hais tias ib tug tshwj xeeb pathogen tau raug txheeb xyuas.Siv raws li tus neeg sawv cev thib ob hauv giardiasis thiab ua ib feem ntawm kev siv tshuaj ntau hauv cov kab mob Helicobacter tau tawm tswv yim.

3-[(5-Nitrofurylidene)amino]-2-oxazolidinone (Furoxone) tshwm sim raws li cov hmoov crystalline daj nrog cov qab qab qab.Nws yog insoluble hauv dej lossis cawv.Furazolidone muaj cov kab mob tua kab mob tawm tsam ntau yam kab mob hauv plab hnyuv, suav nrog S. aureus, E. coli, Salmonella, Shigella, Proteus spp., Enterobacter, thiab Vibrio cholerae.Nws tseem ua haujlwm tawm tsam protozoan Giardia lamblia.Nws raug pom zoo rau kev kho qhov ncauj ntawm cov kab mob los yog protozoaldiarrhea tshwm sim los ntawm cov kab mob uas raug mob.Tus neeg laus noj ntau npaum li cas yog 100 mg 4 zaug ib hnub.
Tsuas yog ib feem me me ntawm qhov ncauj noj tshuaj ntawm furazolidoneis absorbed.Kwv yees li 5% ntawm qhov ncauj koob tshuaj tuaj yeem kuaj pom hauv cov zis hauv daim ntawv ntawm ntau cov metabolites.Qee lub plab zom mov tau raug tshaj tawm nrog nws siv.Cawv yuav tsum zam thaum siv furazolidone vim tias cov tshuaj tuaj yeem inhibit aldehyde dehydrogenase.


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    Furazolidone CAS 67-45-8