Cov khoom

Txhawm rau kom tau txais kev nkag siab txog kev ua kom muaj zog ntawm cov neeg nyob hauv mast cell subpopulations nyob rau hauv ib txwm thiab kab mob ntawm daim tawv nqaij, ib tug tshiab enzyme-histochemical ob thiab triple staining txoj kev tau ua hauj lwm uas tso cai rau nrhiav tau ntawm metachromasia (toluidine xiav) thiab mast cell proteases tryptase thiab chymase nyob rau hauv lub tib cell.Cov seem Cryostat tau siv rau ntawm daim tawv nqaij biopsies los ntawm cov qauv hauv qab no: daim tawv nqaij ib txwm (N = 4), psoriasis (N = 13), atopic eczema (N = 7), lichen planus (N = 6), interferon alpha 2a txhaj tshuaj (N. = 1) ntawm leukemic infiltrate thiab sib xws ntawm daim tawv nqaij ntawm tib tus neeg mob ua ntej thiab tom qab kev kho mob.(i) Cov lej sib npaug ntawm tryptase- thiab chymase-positive mast cells (MCTC) tau txais nyob rau hauv tag nrho cov kab mob thiab cov kab mob hauv papillary thiab reticular dermis, nrog rau peb zaug nce nyob ib ncig ntawm appendages.(ii) Tryptase-positive mast cells (MCT) tsis nyob hauv daim tawv nqaij li qub, tab sis tau nce ntxiv hauv cov kab mob tshwj xeeb hauv cov papillary dermis, inflammatory infiltrate thiab nyob ib ncig ntawm appendages.(iii) Cov cim nce ntawm MCT kuj tau sau tseg ntawm qhov chaw txhaj tshuaj interferon nyob rau hauv cov leukemic infiltrate, tab sis tsis nyob rau hauv daim tawv nqaij ntawm tib tus neeg mob.Cov ntaub ntawv no qhia tias cov kab mob-dependent mast cell dynamics koom nrog tsuas yog MCT nyob rau hauv daim tawv nqaij o thiab MCT cov lej raug tswj los ntawm cov kab mob tshwj xeeb hauv zos cov ntaub so ntswg.