Cov khoom

3-tert-Butoxycarbonylphenylboronic acid, tseem hu ua Boc-phenylboronic acid, yog ib qho tseem ceeb boronic acid derivative nrog cov ntaub ntawv tseem ceeb hauv cov organic synthesis thiab tshuaj chemistry.Ib qho ntawm thawj siv ntawm 3-tert-Butoxycarbonylphenylboronic acid yog raws li ib tug tiv thaiv pab pawg neeg nyob rau hauv cov organic. synthesis.Cov pab pawg tert-butyloxycarbonyl (BOC) feem ntau yog ua haujlwm los tiv thaiv amine ua haujlwm ib ntus thaum muaj kev cuam tshuam ntau yam.Los ntawm kev txuas cov pab pawg BOC mus rau amine moiety, lub reactivity ntawm amine yog attenuated, tso cai rau xaiv cov tshuaj tiv thaiv ntawm lwm txoj hauj lwm ntawm lub molecule.Cov pab pawg BOC tuaj yeem raug tshem tawm yooj yim nyob rau hauv cov mob me me, yog li nthuav tawm cov haujlwm ntawm amine thawj.Qhov kev tiv thaiv pab pawg no ua rau muaj txiaj ntsig zoo ntawm cov organic molecules, xws li tshuaj thiab cov khoom siv ntuj tsim. Tsis tas li ntawd, 3-tert-Butoxycarbonylphenylboronic acid yog ib qho tseem ceeb reagent rau carbon-carbon bond tsim.Boronic acids, suav nrog Boc-phenylboronic acid, nkag mus rau boronate esters thaum reacted nrog nucleophiles, xws li cawv los yog amines.Cov boronate esters no tuaj yeem dhau los ua ntau yam kev hloov pauv, suav nrog Suzuki-Miyaura cross-coupling tshua, Negishi couplings, thiab Stille couplings.Cov tshuaj tiv thaiv no pab tsim cov txheej txheem organic molecules nrog ntau hom kev hloov pauv thiab pab pawg ua haujlwm.Boc-phenylboronic acid yog tshwj xeeb tshaj yog pab tau rau kev qhia phenylboronic acid moiety rau hauv lub hom phiaj molecules. Tsis tas li ntawd, Boc-phenylboronic acid plays lub luag hauj lwm tseem ceeb hauv tshuaj chemistry.Kev ua haujlwm ntawm boronic acid tuaj yeem xaiv kev cuam tshuam nrog diols lossis boronate ester-sensitive functional pawg hauv cov hom phiaj lom neeg, ua rau tsim cov boronate-based enzyme inhibitors thiab receptor ligands.Boc-phenylboronic acid tuaj yeem muab tso rau hauv me me-molecule inhibitors, peptides, lossis prodrugs los muab cov khoom xav tau lossis txhim kho lub hom phiaj tshwj xeeb.Cov boronate-raws li cov tebchaw no tau pom cov lus cog tseg hauv kev kho mob ntawm ntau yam kab mob, suav nrog mob qog noj ntshav, ntshav qab zib, thiab mob.Nws pab pawg BOC ua haujlwm pab pawg tiv thaiv, tso cai rau kev xaiv cov tshuaj tiv thaiv ntawm lwm txoj haujlwm ntawm molecule.Tsis tas li ntawd, boronic acid functionality enables carbon-carbon bond formations, ua kom yooj yim synthesis ntawm complex organic molecules.Tsis tas li ntawd, Boc-phenylboronic acid plays lub luag haujlwm tseem ceeb hauv tshuaj chemistry, qhov twg nws yog siv los tsim cov boronate-based enzyme inhibitors thiab receptor ligands.Zuag qhia tag nrho, Boc-phenylboronic acid yog ib qho tseem ceeb reagent uas pab txhawb rau kev nce qib hauv cov khoom siv hluav taws xob thiab kev tshawb nrhiav tshuaj.