(2S, 3R, 4S, 5S, 6R)-2-(3-(4-((S))-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy 2H-pyran-3,4,5-triol CAS Nr .: 1279691-36-9
| Catalog Number | xwm 93372 |
| Khoom npe | (2S, 3R, 4S, 5S, 6R)-2-(3-(4-((S))-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy 2H-pyran-3,4,5-triol |
| CAS | 1279691-36-9 |
| Molecular Formula | C24H29ClO8 |
| Molecular Luj | 480.94 ib |
| Cov ntaub ntawv khaws cia | Ambient |
Khoom Specification
| Qhov tshwm sim | Dawb hmoov |
| Assay | 99% min |
Cov tshuaj (2S, 3R, 4S, 5S, 6R)-2-(3-(4-(((S))-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2 -methoxy-2H-pyran-3,4,5-triol yog ib tug complex organic molecule uas muaj peev xwm siv nyob rau hauv ntau yam teb, nrog rau cov kws thiab tshuaj chemistry.Cov compound belongs rau cov chav kawm ntawv ntawm pyranopyrans, uas yog cyclic compounds muaj ib tug pyran nplhaib fused. nrog rau lwm lub nplhaib pyran.Lub xub ntiag ntawm ntau lub stereocenters nyob rau hauv nws cov qauv ua rau nws ib tug chiral molecule, lub ntsiab lus nws muaj nyob rau hauv ob enantiomeric cov ntaub ntawv uas muaj peev xwm muaj ntau yam kev ua si lom.Cov yam ntxwv ntawm cov molecule, xws li cov benzyl thiab chlorophenyl pawg, ua ke nrog muaj ntau pawg hydroxyl, qhia tias nws yuav ua rau muaj kev lom zem.Pharmaceutical chemists tuaj yeem tshawb xyuas qhov sib xyaw ua ke uas muaj peev xwm ua cov hmoov txhuas rau kev tsim cov tshuaj tshiab, tshwj xeeb tshaj yog cov hom phiaj cov kab mob uas cuam tshuam nrog cov metabolism hauv carbohydrate.Qhov muaj nyob ntawm pawg (S)-tetrahydrofuran-3-yloxy qhia tias cov compound yuav muaj peev xwm sib cuam tshuam. nrog receptors lossis enzymes koom nrog hauv carbohydrate metabolism los yog kev taw qhia txoj hauv kev.Cov kws tshawb nrhiav tuaj yeem tshawb xyuas nws lub peev xwm los ua tus inhibitor lossis modulator ntawm cov enzymes lossis receptors koom nrog hauv cov txheej txheem no.Tsis tas li ntawd, qhov sib xyaw ua ke ntawm cov txheej txheem tsis yooj yim yuav ua rau nws yog ib tus neeg sib tw tsim nyog rau kev kho tshuaj chemistry optimization los ntawm kev hloov kho cov qauv. Tsis tas li ntawd, lub compound pyranopyran scaffold muaj ntau pawg hydroxyl, uas yog cov pab pawg tseem ceeb hauv kev tsim tshuaj.Cov pab pawg Hydroxyl tuaj yeem koom nrog kev sib koom ua ke ntawm hydrogen bonding, cuam tshuam rau cov khoom sib xyaw solubility, kev ruaj ntseg, thiab cov khoom siv tshuaj pharmacokinetic.Cov kws kho mob tuaj yeem siv cov pab pawg no txhawm rau txhim kho cov khoom sib xyaw ua ke, kev xaiv, thiab lwm yam khoom siv tshuaj.Cov khoom siv sib xyaw ua ke kuj qhia txog kev siv cov ntaub ntawv tshawb fawb thiab cov organic synthesis.Nws txoj kev npaj tshwj xeeb ntawm cov pab pawg ua haujlwm tuaj yeem siv rau kev sib txuas ntawm cov organic tebchaw tshiab nrog cov khoom tshwj xeeb lossis kev ua haujlwm.Tsis tas li ntawd, qhov sib xyaw ua ke tuaj yeem ua lub hauv paus rau kev tsim cov ntaub ntawv tshiab, xws li polymers lossis supramolecular cov qauv, nrog rau kev siv ntau yam kev lag luam.In xaus, cov compound (2S,3R,4S,5S,6R)-2- (3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy-2H-pyran-3,4,5-triol muaj cov qauv tsim cov yam ntxwv uas ua rau nws muaj txiaj ntsig zoo hauv kev siv tshuaj thiab tshuaj chemistry, cov ntaub ntawv tshawb fawb, thiab cov organic synthesis.Nws cov qauv kev sib txawv thiab ntau yam ntawm cov pab pawg ua haujlwm muab sijhawm rau kev tshawb nrhiav hauv kev tshawb nrhiav tshuaj, enzyme modulation, cov ntaub ntawv tsim kho, thiab lwm qhov chaw tshawb fawb.
