Cov khoom

2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone, feem ntau hu ua TMS-D-glucose, yog ntau yam sib xyaw uas pom cov ntawv thov hauv ntau yam kev tshawb fawb, suav nrog cov organic synthesis, carbohydrate chemistry, thiab tshuaj chemistry. TMS-D-glucose yog tshwj xeeb tshaj yog muaj txiaj ntsig hauv cov organic synthesis vim nws ua haujlwm pab pawg tiv thaiv rau hydroxyl (OH) pawg ua haujlwm hauv carbohydrates.Los ntawm kev qhia cov pab pawg trimethylsilyl (TMS) mus rau pawg hydroxyl ntawm cov piam thaj, cov khoom sib xyaw ua kom ruaj khov thiab tsis tshua muaj zog, tso cai rau kev xaiv cov kev hloov pauv ntawm cov pab pawg hydroxyl tshwj xeeb thaum ua rau lwm tus tsis muaj kev cuam tshuam thaum hloov tshuaj lom neeg tom ntej.Lub tswv yim tiv thaiv kev tiv thaiv no yog siv dav hauv cov khoom noj carbohydrate chemistry kom ua tiav cov kev xav tau regioselectivity thiab stereochemistry hauv kev sib xyaw ntawm cov carbohydrates nyuaj, glycoconjugates, thiab cov khoom ntuj tsim.In analytical chemistry, TMS-D-glucose yog siv los ua ib qho derivatization reagent rau kev tshawb nrhiav thiab quantity. ntawm carbohydrates.Los ntawm kev hloov cov carbohydrates rau hauv lawv cov trimethylsilyl derivatives, lawv cov volatility thiab thermal stability txhim kho, ua rau lawv haum rau kev tsom xam los ntawm roj chromatography (GC) thiab huab hwm coj spectrometry (MS).Cov txheej txheem derivatization no txhim kho qhov kev tshawb pom rhiab heev, txhim kho kev sib cais kev ua haujlwm, thiab ua kom muaj kev txheeb xyuas ntau yam carbohydrates hauv cov khoom sib xyaw ua ke, xws li cov qauv tshuaj lom neeg lossis cov khoom noj khoom haus.TMS-D-glucose kuj pom cov ntawv thov hauv kev sib xyaw ntawm cov tshuaj reagents tshwj xeeb thiab tshuaj ntsuam xyuas.Nws qhov tshwj xeeb reactivity thiab stability ua rau nws yog ib qho tseem ceeb pib cov khoom siv rau kev npaj ntawm lwm cov carbohydrate-derived compounds.Cov kws tshawb fawb tuaj yeem hloov kho cov trimethylsilyl moiety lossis hloov cov piam thaj moiety los tsim cov khoom sib xyaw nrog cov khoom tshwj xeeb, xws li cov tshuaj fluorescent probes, enzyme inhibitors, lossis cov tshuaj sib tw.Cov derivatives no tuaj yeem ua haujlwm nyob rau hauv ntau yam kev tshawb fawb lom neeg thiab biomedical, suav nrog kev tshuaj ntsuam xyuas, kev txhim kho tshuaj, lossis kev nkag siab txog kev sib cuam tshuam ntawm carbohydrate-protein.Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum xav txog tias TMS-D-glucose, zoo li lwm yam tshuaj lom neeg, yuav tsum tau tuav kom zoo thiab kev nyab xeeb. cov kev ceev faj.Cov kws tshawb fawb yuav tsum xyuas kom muaj qhov cua txaus thiab siv cov cuab yeej tiv thaiv tus kheej tsim nyog thaum ua haujlwm nrog qhov sib xyaw no txhawm rau tiv thaiv kev phom sij rau kev noj qab haus huv.Tsis tas li ntawd, raws li nrog rau cov tshuaj reagent, purity, thiab zoo ntawm TMS-D-glucose yog qhov tseem ceeb kom tau txais cov txiaj ntsig zoo thiab rov tsim dua tshiab. Hauv cov ntsiab lus, TMS-D-glucose yog ib qho tseem ceeb hauv cov organic synthesis, carbohydrate chemistry, thiab tshuaj chemistry.Nws lub peev xwm los xaiv kev tiv thaiv hydroxyl pawg hauv carbohydrates, nws siv tau hauv kev tsom xam carbohydrate, thiab nws cov txiaj ntsig hauv kev sib xyaw ntawm cov tshuaj reagents tshwj xeeb ua rau nws yog ib qho tseem ceeb hauv ntau yam kev qhuab qhia.Los ntawm kev siv TMS-D-qabzib, cov kws tshawb fawb tuaj yeem ua tiav lawv cov kev tshawb fawb hauv cov tshuaj carbohydrate, glycoscience, thiab lwm yam kev lag luam, pab txhawb rau kev tsim cov tebchaw tshiab, kuaj mob, thiab cov tshuaj kho mob.