2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-ib CAS: 1044871-04-6
Catalog Number | xwm 90961 |
Khoom npe | 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-ib |
CAS | 1044871-04-6 |
Molecular Formula | C24H29N3O4 |
Molecular Luj | 423.5 ib |
Cov ntaub ntawv khaws cia | |
Harmonized tariff Code |
Khoom Specification
Qhov tshwm sim | |
Assay | |
Boiling point | 612.6 ± 65.0 ° C (Tshaj tawm) |
Qhov ntom | 1.25 ± 0.1 g / cm3 (Tshaj tawm) |
Acidity coefficient | (pKa) 9.54 ± 0.20 (Predicted) |
RVX-297 yog ib qho muaj zog heev, hais lus nquag BET inhibitor xaiv rau BD2.IC50s ntawm RVX-297 rau BRD2(BD2), BRD3(BD2), thiab BRD4(BD2) yog 0.08, 0.05, thiab 0.02 μM, feem.RVX-297 inhibits qhov kev qhia ntawm ntau lub cev tiv thaiv kab mob inflammatory genes.Kev ua tau zoo ntawm RVX-297 hauv cov qauv ua ntej ntawm kev mob o thiab autoimmunity.
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